Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms.
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Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal AntibodyA Modular Vaccine Development Platform Based on Sortase-Mediated Site-Specific Tagging of Antigens onto Virus-Like ParticlesEnterovirus 71 infection and vaccines.Effective in vivo therapeutic IgG antibody against VP3 of enterovirus 71 with receptor-competing activitySubviral particle as vaccine and vaccine platform.Cryo-electron microscopy study of insect cell-expressed enterovirus 71 and coxsackievirus a16 virus-like particles provides a structural basis for vaccine development.Novel recombinant chimeric virus-like particle is immunogenic and protective against both enterovirus 71 and coxsackievirus A16 in mice.Structural basis for the development of avian virus capsids that display influenza virus proteins and induce protective immunity.Characterization of the antibody response against EV71 capsid proteins in Chinese individuals by NEIBM-ELISA.A Broadly Cross-protective Vaccine Presenting the Neighboring Epitopes within the VP1 GH Loop and VP2 EF Loop of Enterovirus 71.Single Neutralizing Monoclonal Antibodies Targeting the VP1 GH Loop of Enterovirus 71 Inhibit both Virus Attachment and Internalization during Viral EntryEV71 virus-like particles produced by co-expression of capsid proteins in yeast cells elicit humoral protective response against EV71 lethal challengeProtection against lethal enterovirus 71 challenge in mice by a recombinant vaccine candidate containing a broadly cross-neutralizing epitope within the VP2 EF loop.The application of virus-like particles as vaccines and biological vehicles.The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro.Coxsackievirus A16 utilizes cell surface heparan sulfate glycosaminoglycans as its attachment receptor.A shared N-terminal hydrophobic tail for the formation of nanoparticulates.Generation and characterization of a protective mouse monoclonal antibody against human enterovirus 71.Development of a Surrogate Neutralization Assay for Norovirus Vaccine Evaluation at the Cellular Level.Structure, Immunogenicity, and Protective Mechanism of an Engineered Enterovirus 71-Like Particle Vaccine Mimicking 80S Empty Capsid.Etiology, pathogenesis, antivirals and vaccines of hand, foot, and mouth disease
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Chimeric virus-like particle vaccines displaying conserved enterovirus 71 epitopes elicit protective neutralizing antibodies in mice through divergent mechanisms.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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Chimeric virus-like particle v ...... through divergent mechanisms.
@en
Chimeric virus-like particle v ...... through divergent mechanisms.
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label
Chimeric virus-like particle v ...... through divergent mechanisms.
@en
Chimeric virus-like particle v ...... through divergent mechanisms.
@nl
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Chimeric virus-like particle v ...... through divergent mechanisms.
@en
Chimeric virus-like particle v ...... through divergent mechanisms.
@nl
P2093
P2860
P356
P1433
P1476
Chimeric virus-like particle v ...... through divergent mechanisms.
@en
P2093
Jinping Shi
Liangliang Kong
Qingwei Liu
Xiaoli Wang
Yunfang Zhang
Zhiqiang Ku
P2860
P356
10.1128/JVI.01848-13
P407
P577
2013-10-16T00:00:00Z