A GNAS mutation found in pancreatic intraductal papillary mucinous neoplasms induces drastic alterations of gene expression profiles with upregulation of mucin genes.
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Pancreatic adenocarcinoma pathology: changing "landscape"Deep sequencing of cancer-related genes revealed GNAS mutations to be associated with intraductal papillary mucinous neoplasms and its main pancreatic duct dilation.GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma.Expansion of epigenetic alterations in EFEMP1 promoter predicts malignant formation in pancreatobiliary intraductal papillary mucinous neoplasmsEndoscopic ultrasound-guided fine-needle aspiration plus KRAS and GNAS mutation in malignant intraductal papillary mucinous neoplasm of the pancreas.Mucins in pancreatic cancer: biological role, implications in carcinogenesis and applications in diagnosis and therapy.GNAS(R201H) and Kras(G12D) cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm.GNAS mutations are present in colorectal traditional serrated adenomas, serrated tubulovillous adenomas and serrated adenocarcinomas with adverse prognostic features.Microinsertions in PRKACA cause activation of the protein kinase A pathway in cardiac myxoma.Ramifications of Secreted Mucin MUC5AC in Malignant Journey: A Holistic View.RNF43 mutation frequently occurs with GNAS mutation and mucin hypersecretion in intraductal papillary neoplasms of the bile duct.[Classification and malignant potential of pancreatic cystic tumors].Activating mutations of GNAS and KRAS in cystic fluid can help detect intraductal papillary mucinous neoplasms of the pancreas.PRDM14 is overexpressed in chronic pancreatitis prior to pancreatic cancer
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A GNAS mutation found in pancreatic intraductal papillary mucinous neoplasms induces drastic alterations of gene expression profiles with upregulation of mucin genes.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 February 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A GNAS mutation found in pancr ...... h upregulation of mucin genes.
@en
A GNAS mutation found in pancr ...... h upregulation of mucin genes.
@nl
type
label
A GNAS mutation found in pancr ...... h upregulation of mucin genes.
@en
A GNAS mutation found in pancr ...... h upregulation of mucin genes.
@nl
prefLabel
A GNAS mutation found in pancr ...... h upregulation of mucin genes.
@en
A GNAS mutation found in pancr ...... h upregulation of mucin genes.
@nl
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A GNAS mutation found in pancr ...... th upregulation of mucin genes
@en
P2093
Etsuko Tanji
Fuyuhiko Motoi
Hirotake Komatsu
Michiaki Unno
Naoaki Sakata
Takeshi Aoki
Yu Katayose
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10.1371/JOURNAL.PONE.0087875
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2014-02-03T00:00:00Z