Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease.
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Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the BrainMammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease.Computational modeling of sphingolipid metabolism.The Molecular Mechanism of Amyloid β42 Peptide Toxicity: The Role of Sphingosine Kinase-1 and Mitochondrial SirtuinsA facile stable-isotope dilution method for determination of sphingosine phosphate lyase activity.Resveratrol and its oligomers: modulation of sphingolipid metabolism and signaling in disease.Sphingosine-1-phosphate restores endothelial barrier integrity in ovarian hyperstimulation syndrome.Altered Sphingolipid Balance in Capillary Cerebral Amyloid Angiopathy.Crosstalk between sphingolipids and vitamin D3: potential role in the nervous system.Sphingosine 1-phosphate receptor 1 is required for retinal ganglion cell survival after optic nerve trauma.Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements.Loss of Sphingosine Kinase Alters Life History Traits and Locomotor Function in Caenorhabditis elegans.De novo Synthesis of Sphingolipids Is Defective in Experimental Models of Huntington's Disease.Alpha-synuclein alters differently gene expression of Sirts, PARPs and other stress response proteins: implications for neurodegenerative disorders.Neuronal sphingosine kinase 2 subcellular localization is altered in Alzheimer's disease brain.Sphingolipid Metabolism: A New Therapeutic Opportunity for Brain Degenerative Disorders.Particular CSF sphingolipid patterns identify iNPH and AD patients
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Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer's disease.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Reduced sphingosine kinase-1 a ...... naling in Alzheimer's disease.
@en
Reduced sphingosine kinase-1 a ...... naling in Alzheimer's disease.
@nl
type
label
Reduced sphingosine kinase-1 a ...... naling in Alzheimer's disease.
@en
Reduced sphingosine kinase-1 a ...... naling in Alzheimer's disease.
@nl
prefLabel
Reduced sphingosine kinase-1 a ...... naling in Alzheimer's disease.
@en
Reduced sphingosine kinase-1 a ...... naling in Alzheimer's disease.
@nl
P2093
P2860
P50
P356
P1476
Reduced sphingosine kinase-1 a ...... naling in Alzheimer's disease.
@en
P2093
Catherine Gentil
Charles Duyckaerts
Claude Alain Maurage
Johnatan Ceccom
Najat Loukh
Valérie Lauwers-Cances
Yvan Nicaise
P2860
P2888
P356
10.1186/2051-5960-2-12
P577
2014-01-27T00:00:00Z
P5875
P6179
1035565154