Emerging roles of Orai3 in pathophysiology. - Wikidata - awgldk - TriplyDB

Emerging roles of Orai3 in pathophysiology.

Emerging roles of Orai3 in pathophysiology.

http://www.wikidata.org/entity/Q37554601

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Altered expression of stromal interaction molecule (STIM)-calcium release-activated calcium channel protein (ORAI) and inositol 1,4,5-trisphosphate receptors (IP3Rs) in cancer: will they become a new battlefield for oncotherapy?The role of STIM and ORAI proteins in phagocytic immune cells MycN promotes TRPM7 expression and cell migration in neuroblastoma through a process that involves polyamines.Leukotriene-C4 synthase, a critical enzyme in the activation of store-independent Orai1/Orai3 channels, is required for neointimal hyperplasia.STIM and Orai proteins as novel targets for cancer therapy. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis.Failure of Elevating Calcium Induces Oxidative Stress Tolerance and Imparts Cisplatin Resistance in Ovarian Cancer Cells.ORAI2 modulates store-operated calcium entry and T cell-mediated immunity ORAI Calcium Channels.p53 and Ca(2+) signaling from the endoplasmic reticulum: partners in anti-cancer therapies.Cardiovascular and Hemostatic Disorders: Role of STIM and Orai Proteins in Vascular Disorders.Arachidonic acid-induced Ca2+ entry and migration in a neuroendocrine cancer cell line.

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Emerging roles of Orai3 in pathophysiology.

http://www.wikidata.org/entity/Q37554601

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article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 21 May 2013

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vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

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name

Emerging roles of Orai3 in pathophysiology.

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Emerging roles of Orai3 in pathophysiology.

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type

label

Emerging roles of Orai3 in pathophysiology.

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Emerging roles of Orai3 in pathophysiology.

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prefLabel

Emerging roles of Orai3 in pathophysiology.

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Emerging roles of Orai3 in pathophysiology.

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Emerging roles of Orai3 in pathophysiology.

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Judith A Stolwijk

http://www.w3.org/2001/XMLSchema#string

Mohamed Trebak

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Rachel L Newton

http://www.w3.org/2001/XMLSchema#string

Rajender K Motiani

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Xuexin Zhang

http://www.w3.org/2001/XMLSchema#string

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Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

Orai1 and STIM reconstitute store-operated calcium channel function

Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1

Orai1 is an essential pore subunit of the CRAC channel

Store-independent activation of Orai1 by SPCA2 in mammary tumors

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

SARAF inactivates the store operated calcium entry machinery to prevent excess calcium refilling

CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry

STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

Amplification of CRAC current by STIM1 and CRACM1 (Orai1)

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392-401

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scholarly article

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10.4161/CHAN.24960

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5

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7

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2013-05-21T00:00:00Z

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236883655

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23695829

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pathophysiology

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3913762

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