Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1
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1.12 Å resolution crystal structure of the catalytic domain of the plasmid-mediated colistin resistance determinant MCR-2.Detection of Colistin-Resistant MCR-1-Positive Escherichia coli by Use of Assays Based on Inhibition by EDTA and Zeta Potential.MCR-1 Inhibition with Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Sensitivity to Polymyxin in Escherichia coli.Balancing mcr-1 expression and bacterial survival is a delicate equilibrium between essential cellular defence mechanisms.Comparative analysis of phosphoethanolamine transferases involved in polymyxin resistance across ten clinically relevant gram-negative bacteria.Mechanistic insights into transferable polymyxin resistance among gut bacteria.An Evolutionarily Conserved Mechanism for Intrinsic and Transferable Polymyxin Resistance.Defining ICR-Mo, an intrinsic colistin resistance determinant from Moraxella osloensis.Emergence of a novel mobile colistin resistance gene, mcr-8, in NDM-producing Klebsiella pneumoniae.
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Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from Crystal Structures of the Catalytic Domain of MCR-1
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 January 2017
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Insights into the Mechanistic ...... the Catalytic Domain of MCR-1
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Insights into the Mechanistic ...... the Catalytic Domain of MCR-1.
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Insights into the Mechanistic ...... the Catalytic Domain of MCR-1
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Insights into the Mechanistic ...... the Catalytic Domain of MCR-1.
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Insights into the Mechanistic ...... the Catalytic Domain of MCR-1
@en
Insights into the Mechanistic ...... the Catalytic Domain of MCR-1.
@nl
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Insights into the Mechanistic ...... the Catalytic Domain of MCR-1
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Edward Portal
James Spencer
Jianzhong Shen
Pannika R Niumsup
Qiu E Yang
Uttapoln Tansawai
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P2888
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10.1038/SREP39392
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P577
2017-01-06T00:00:00Z