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Purinergic signalling and diabetesPurinergic signalling in endocrine organsPannexin 1 is required for full activation of insulin-stimulated glucose uptake in adipocytes.Lipolysis in adipocytes.Impaired glucose tolerance in the absence of adenosine A1 receptor signalingUltrasound associated with caffeine increases basal and beta-adrenoceptor response in adipocytes isolated from subcutaneous adipose tissue in pigs.Dual A1/A2B Receptor Blockade Improves Cardiac and Renal Outcomes in a Rat Model of Heart Failure with Preserved Ejection Fraction.The functional state of hormone-sensitive adenylyl cyclase signaling system in diabetes mellitusDiminished adenosine A1 receptor expression in pancreatic α-cells may contribute to the pathology of type 1 diabetes.Current clinical evidence on pioglitazone pharmacogenomics.A1 adenosine receptor negatively modulates coronary reactive hyperemia via counteracting A2A-mediated H2O2 production and KATP opening in isolated mouse heartsElevated concentrations of plasma adenosine in obese children.Adenosine A1 modulators: a patent update (2008 to present).Moonlighting adenosine deaminase: a target protein for drug development.Deletion of CD73 promotes dyslipidemia and intramyocellular lipid accumulation in muscle of mice.Lipolysis and lipases in white adipose tissue - An update.Partial Adenosine A1 Agonist in Heart Failure.Reduction of free fatty acids, safety, and pharmacokinetics of oral GS-9667, an A(1) adenosine receptor partial agonist.Purinergic Receptors in Adipose Tissue As Potential Targets in Metabolic Disorders.Biochemical and Pharmacological Role of A1 Adenosine Receptors and Their Modulation as Novel Therapeutic Strategy.Chronic caffeine intake decreases circulating catecholamines and prevents diet-induced insulin resistance and hypertension in rats.The involvement of purinergic signalling in obesity.Safety and Tolerability of Neladenoson Bialanate, a Novel Oral Partial Adenosine A1 Receptor Agonist, in Patients With Chronic Heart Failure.Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A1 adenosine receptor: role in diabetes and obesity.
@en
A1 adenosine receptor: role in diabetes and obesity.
@nl
type
label
A1 adenosine receptor: role in diabetes and obesity.
@en
A1 adenosine receptor: role in diabetes and obesity.
@nl
prefLabel
A1 adenosine receptor: role in diabetes and obesity.
@en
A1 adenosine receptor: role in diabetes and obesity.
@nl
P2093
P1476
A1 adenosine receptor: role in diabetes and obesity.
@en
P2093
Arvinder K Dhalla
Jeffrey W Chisholm
Luiz Belardinelli
P304
P356
10.1007/978-3-540-89615-9_9
P577
2009-01-01T00:00:00Z