Receptors for human alpha and beta interferon but not for gamma interferon are specified by human chromosome 21.
about
Alpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testesLigand-induced IFN gamma receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91)The gene for cystathionine beta-synthase (CBS) maps to the subtelomeric region on human chromosome 21q and to proximal mouse chromosome 17Molecular genetics of human chromosome 21.Down syndrome: characterisation of a case with partial trisomy of chromosome 21 owing to a paternal balanced translocation (15;21) (q26;q22.1) by FISH.Genetic associations in type I interferon related pathways with autoimmunityHuman chromosomes 6 and 21 are required for sensitivity to human interferon gammaTransport of exogenous growth factors and cytokines to the cytosol and to the nucleus.Down's syndrome and the thyroid.Libraries for each human chromosome, constructed from sorter-enriched chromosomes by using linker-adaptor PCR.Regional localization of DNA sequences on chromosome 21 using somatic cell hybridsPhysical mapping around the Alzheimer disease locus on the proximal long arm of chromosome 21The gene for the human immune interferon receptor is located on chromosome 6.Human Cu/Zn superoxide dismutase gene family: molecular structure and characterization of four Cu/Zn superoxide dismutase-related pseudogenesPosttranscriptional regulation of beta interferon expression in erythroid Friend cells treated with gamma interferon.Distribution of interspersed repeats (Alu and Kpn) on NotI restriction fragments of human chromosome 21Regulation of the interferon-inducible IFI-78K gene, the human equivalent of the murine Mx gene, by interferons, double-stranded RNA, certain cytokines, and viruses.Beta and gamma interferons act synergistically to produce an antiviral state in cells resistant to both interferons individually.Quantitative proteomics characterization of a mouse embryonic stem cell model of Down syndrome.Rapid and transient rise in diacylglycerol concentration in Daudi cells exposed to interferon.Transmembrane signaling by the alpha subunit of the type I interferon receptor is essential for activation of the JAK kinases and the transcriptional factor ISGF3.Expression and signaling specificity of the IFNAR chain of the type I interferon receptor complexMononucleotide repeat polymorphism in the APP geneA polymorphic microsatellite repeat sequence on chromosome 21 (D21S80).The extracellular domain of the human interferon gamma receptor interacts with a species-specific signal transducerDifferential tyrosine phosphorylation of the IFNAR chain of the type I interferon receptor and of an associated surface protein in response to IFN-alpha and IFN-betaIdentification of a domain in the beta subunit of the type I interferon (IFN) receptor that exhibits a negative regulatory effect in the growth inhibitory action of type I IFNs.Polymerase chain reactions with alphoid-repeat primers in combination with Alu or LINEs primers, generate chromosome-specific DNA fragments.Transchromosomic cell model of Down syndrome shows aberrant migration, adhesion and proteome response to extracellular matrix.T cell activation deficiency associated with an aberrant pattern of protein tyrosine phosphorylation after CD3 perturbation in Down's syndrome.
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P2860
Receptors for human alpha and beta interferon but not for gamma interferon are specified by human chromosome 21.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on September 1984
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Receptors for human alpha and ...... cified by human chromosome 21.
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Receptors for human alpha and ...... cified by human chromosome 21.
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type
label
Receptors for human alpha and ...... cified by human chromosome 21.
@en
Receptors for human alpha and ...... cified by human chromosome 21.
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prefLabel
Receptors for human alpha and ...... cified by human chromosome 21.
@en
Receptors for human alpha and ...... cified by human chromosome 21.
@nl
P2093
P2860
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P1476
Receptors for human alpha and ...... cified by human chromosome 21.
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A Raziuddin
F H Ruddle
F H Sarkar
R Dutkowski
P2860
P304
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10.1073/PNAS.81.17.5504
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P577
1984-09-01T00:00:00Z