Hierarchical assembly of presynaptic components in defined C. elegans synapses.
about
mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle dockingLocal F-actin network links synapse formation and axon branchingFunctional and spatial analysis of C. elegans SYG-1 and SYG-2, orthologs of the Neph/nephrin cell adhesion module directing selective synaptogenesisThe presynaptic active zoneELKS2alpha/CAST deletion selectively increases neurotransmitter release at inhibitory synapsesUnderstanding Synaptogenesis and Functional Connectome in C. elegans by Imaging TechnologyPresynaptic spinophilin tunes neurexin signalling to control active zone architecture and functionUNC-16 (JIP3) Acts Through Synapse-Assembly Proteins to Inhibit the Active Transport of Cell Soma Organelles to Caenorhabditis elegans Motor Neuron Axons.Synapse-Assembly Proteins Maintain Synaptic Vesicle Cluster Stability and Regulate Synaptic Vesicle Transport in Caenorhabditis elegans.Differential expression of liprin-α family proteins in the brain suggests functional diversificationIdentification and glycerol-induced correction of misfolding mutations in the X-linked mental retardation gene CASKSYD-1C, UNC-40 (DCC) and SAX-3 (Robo) function interdependently to promote axon guidance by regulating the MIG-2 GTPaseCdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASKSynaptic scaffolding protein SYD-2 clusters and activates kinesin-3 UNC-104 in C. elegans.An Arf-like small G protein, ARL-8, promotes the axonal transport of presynaptic cargoes by suppressing vesicle aggregationDynamic mechanisms of neuroligin-dependent presynaptic terminal assembly in living cortical neuronsDeep phenotyping unveils hidden traits and genetic relations in subtle mutants.Profiling synaptic proteins identifies regulators of insulin secretion and lifespan.The ubiquitin ligase RPM-1 and the p38 MAPK PMK-3 regulate AMPA receptor traffickingPresynaptic CaV2 calcium channel traffic requires CALF-1 and the alpha(2)delta subunit UNC-36A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila.Drosophila Syd-1, liprin-α, and protein phosphatase 2A B' subunit Wrd function in a linear pathway to prevent ectopic accumulation of synaptic materials in distal axons.The presynaptic dense projection of the Caenorhabditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD-2/liprin and UNC-10/RIM-dependent interactionsThree Drosophila liprins interact to control synapse formation.Trio, a Rho Family GEF, Interacts with the Presynaptic Active Zone Proteins Piccolo and Bassoon.The scaffolding protein SYD-2/Liprin-α regulates the mobility and polarized distribution of dense-core vesicles in C. elegans motor neuronsA conserved juxtacrine signal regulates synaptic partner recognition in Caenorhabditis elegans.Transcriptional coordination of synaptogenesis and neurotransmitter signaling.Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.Presynaptic active zones in invertebrates and vertebrates.The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegansSynaptic vesicle clustering requires a distinct MIG-10/Lamellipodin isoform and ABI-1 downstream from Netrin.Loss of syd-1 from R7 neurons disrupts two distinct phases of presynaptic developmentLiprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmissionDistinct isoforms of the RFX transcription factor DAF-19 regulate ciliogenesis and maintenance of synaptic activity.ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains.Building a synapse: lessons on synaptic specificity and presynaptic assembly from the nematode C. elegansCell biology in neuroscience: cellular and molecular mechanisms underlying presynapse formation.Maturation of active zone assembly by Drosophila BruchpilotThe role of the ubiquitin proteasome system in synapse remodeling and neurodegenerative diseases.
P2860
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P2860
Hierarchical assembly of presynaptic components in defined C. elegans synapses.
description
2006 nî lūn-bûn
@nan
2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
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2006年學術文章
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2006年學術文章
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name
Hierarchical assembly of presynaptic components in defined C. elegans synapses.
@en
Hierarchical assembly of presynaptic components in defined C. elegans synapses.
@nl
type
label
Hierarchical assembly of presynaptic components in defined C. elegans synapses.
@en
Hierarchical assembly of presynaptic components in defined C. elegans synapses.
@nl
prefLabel
Hierarchical assembly of presynaptic components in defined C. elegans synapses.
@en
Hierarchical assembly of presynaptic components in defined C. elegans synapses.
@nl
P2093
P2860
P356
P1433
P1476
Hierarchical assembly of presynaptic components in defined C. elegans synapses.
@en
P2093
Emily K Lehrman
Justin G Crump
Maulik R Patel
Vivian Y Poon
P2860
P2888
P304
P356
10.1038/NN1806
P407
P577
2006-11-19T00:00:00Z