Accumulation of DNA strand breaks and methotrexate cytotoxicity.
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Methotrexate Is a JAK/STAT Pathway InhibitorA comprehensive molecular interaction map for rheumatoid arthritis.Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakageAdding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report.Adipose-derived stem cells retain their regenerative potential after methotrexate treatment.Transfer of resistance traits from carrot into tobacco by asymmetric somatic hybridization: Regeneration of fertile plants.How a replication origin and matrix attachment region accelerate gene amplification under replication stress in mammalian cells.The origins of DNA breaks: a consequence of DNA damage, DNA repair, or apoptosis?Brazilin isolated from Caesalpinia sappan L. inhibits rheumatoid arthritis activity in a type-II collagen induced arthritis mouse modelA proteomic profile of synoviocyte lesions microdissected from formalin-fixed paraffin-embedded synovial tissues of rheumatoid arthritis.Effect of methotrexate on cerebellar development in infant ratsPI3K inhibition synergizes with glucocorticoids but antagonizes with methotrexate in T-cell acute lymphoblastic leukemiaMechanism of cytotoxicity of 5,10-dideazatetrahydrofolic acid in human ovarian carcinoma cells in vitro and modulation of the drug activity by folic or folinic acid.Uracil-DNA glycosylase inhibitor of bacteriophage PBS2: cloning and effects of expression of the inhibitor gene in Escherichia coli.Selective killing of preneoplastic and neoplastic cells by methotrexate with leucovorinUbiquitous, heritable damage in cell populations that survive treatment with methotrexate.DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways.Methotrexate in rheumatoid arthritis: can current knowledge and experience justify its use as a first-line disease-modifying agent?Effect of cycloheximide on development of methotrexate resistance of Chinese hamster ovary cells treated with inhibitors of DNA synthesis.Transient inhibition of DNA synthesis results in increased dihydrofolate reductase synthesis and subsequent increased DNA content per cellGenotoxicity of pemetrexed in human peripheral blood lymphocytesA comparison of vitamin A and leucovorin for the prevention of methotrexate-induced micronuclei production in rat bone marrowFolylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance.DNA fragmentation in permeabilized cells.mTORC1 Inhibition Induces Resistance to Methotrexate and 6-Mercaptopurine in Ph+ and Ph-like B-ALL.Isolation and characterisation of an antifolate insensitive (afi1) mutant of Arabidopsis thaliana.Effect of methotrexate on the survival of human lymphocyte cultures carrying MTHFR 677 (C>T) and MTHFR 1298 (A>C) mutations.Methotrexate induced apoptotic and necrotic chromatin changes in rat myeloid leukemia cells.20th-century advances in drug therapy in oncology--Part I.
P2860
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P2860
Accumulation of DNA strand breaks and methotrexate cytotoxicity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1984
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Accumulation of DNA strand breaks and methotrexate cytotoxicity.
@en
Accumulation of DNA strand breaks and methotrexate cytotoxicity.
@nl
type
label
Accumulation of DNA strand breaks and methotrexate cytotoxicity.
@en
Accumulation of DNA strand breaks and methotrexate cytotoxicity.
@nl
prefLabel
Accumulation of DNA strand breaks and methotrexate cytotoxicity.
@en
Accumulation of DNA strand breaks and methotrexate cytotoxicity.
@nl
P2860
P356
P1476
Accumulation of DNA strand breaks and methotrexate cytotoxicity.
@en
P2093
P2860
P304
P356
10.1073/PNAS.81.18.5694
P407
P577
1984-09-01T00:00:00Z