Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score - Wikidata - awgldk - TriplyDB

Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score

Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score

http://www.wikidata.org/entity/Q37570427

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PrEMeR-CG: inferring nucleotide level DNA methylation values from MethylCap-seq data.Network Biomarkers Constructed from Gene Expression and Protein-Protein Interaction Data for Accurate Prediction of Leukemia Higher HOPX expression is associated with distinct clinical and biological features and predicts poor prognosis in de novo acute myeloid leukemia SMG1 acts as a novel potential tumor suppressor with epigenetic inactivation in acute myeloid leukemia.Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification.Acute myeloid leukemia: 2014 update on risk-stratification and management.Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia Prognostic value of CD56 in patients with acute myeloid leukemia: a meta-analysis.Identification of major factors associated with failed clinical molecular oncology testing performed by next generation sequencing (NGS).Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics.Mitogen-activated protein kinase binding protein 1 (MAPKBP1) is an unfavorable prognostic biomarker in cytogenetically normal acute myeloid leukemia.DNA methylation and childhood asthma in the inner city GPX3 hypermethylation serves as an independent prognostic biomarker in non-M3 acute myeloid leukemia.DNMT3A R882 Mutations Predict a Poor Prognosis in AML: A Meta-Analysis From 4474 Patients Effect of genetic profiling on prediction of therapeutic resistance and survival in adult acute myeloid leukemia.Targeting leukemia stem cells in vivo with antagomiR-126 nanoparticles in acute myeloid leukemia An integrative study on the impact of highly differentially methylated genes on expression and cancer etiology An mRNA expression signature for prognostication in de novo acute myeloid leukemia patients with normal karyotype.Hypomethylation of TET2 Target Genes Identifies a Curable Subset of Acute Myeloid Leukemia.Hematologic Recovery after Pretransplant Chemotherapy Does Not Influence Survival after Allogeneic Hematopoietic Cell Transplantation in Acute Myeloid Leukemia Patients.A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia A three-gene expression-based risk score can refine the European LeukemiaNet AML classification.WDR5 high expression and its effect on tumorigenesis in leukemia.Clinical implications of genome-wide DNA methylation studies in acute myeloid leukemia.Frontline therapy of AML: should the older patient be treated differently?Acute myeloid leukemia and myelodysplastic syndromes in older adults.Diagnosing and following adult patients with acute myeloid leukaemia in the genomic age.Pan-cancer patterns of DNA methylation.Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia Pharmacokinetics, pharmacodynamics and clinical efficacy of pertuzumab in breast cancer therapy.MicroRNAs in Myeloid Hematological Malignancies.High expression of CPNE3 predicts adverse prognosis in acute myeloid leukemia.Validation of risk stratification models in acute myeloid leukemia using sequencing-based molecular profiling.Frontline treatment of acute myeloid leukemia in adults.Prognostic significance of NPM1 mutation-modulated microRNA-mRNA regulation in acute myeloid leukemia.Acute myeloid leukemia: 2016 Update on risk-stratification and management.A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome.Predicting Chemotherapy Resistance in AML.Characterization of the novel protein KIAA0564 (Von Willebrand Domain-containing Protein 8).A 4-gene expression score associated with high levels of Wilms Tumor-1 (WT1) expression is an adverse prognostic factor in acute myeloid leukaemia.

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Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score

http://www.wikidata.org/entity/Q37570427

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 30 December 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Epigenetics meets genetics in ...... ct of a novel seven-gene score

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Epigenetics meets genetics in ...... t of a novel seven-gene score.

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Epigenetics meets genetics in ...... ct of a novel seven-gene score

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Epigenetics meets genetics in ...... t of a novel seven-gene score.

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Epigenetics meets genetics in ...... ct of a novel seven-gene score

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Epigenetics meets genetics in ...... t of a novel seven-gene score.

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JCO.2013.50.6337

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Journal of Clinical Oncology

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Epigenetics meets genetics in ...... ct of a novel seven-gene score

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Andrew J Carroll

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Ann-Kathrin Eisfeld

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Bayard L Powell

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Christoph Plass

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Constance Bär

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David Frankhouser

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Deedra Nicolet

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Donna Bucci

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Heiko Becker

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John P Curfman

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P2860

DNA methylation and microRNA dysregulation in cancer

DNMT3A Mutations in Acute Myeloid Leukemia

Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated gene- and microRNA-expression signatures: a Cancer and Leukemia Group B study.

Age-related prognostic impact of different types of DNMT3A mutations in adults with primary cytogenetically normal acute myeloid leukemia

RUNX1 mutations are associated with poor outcome in younger and older patients with cytogenetically normal acute myeloid leukemia and with distinct gene and MicroRNA expression signatures.

CpG islands and the regulation of transcription

A genome-wide scan for common alleles affecting risk for autism

Functions of DNA methylation: islands, start sites, gene bodies and beyond

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.

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548-556

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10.1200/JCO.2013.50.6337

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6

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32

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Stefano Volinia

Klaus H Metzeler

Ann-Kathrin Eisfeld

Clara D. Bloomfield

Krzysztof Mrózek

Jessica Kohlschmidt

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2013-12-30T00:00:00Z

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24378410

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