Critical roles for SoxC transcription factors in development and cancer.
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Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitorsThe crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism for positional interdependence in DNA recognitionHippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liverUpregulation of SOX4 antagonizes cellular senescence in esophageal squamous cell carcinomaSox4 links tumor suppression to accelerated aging in mice by modulating stem cell activationEvolutionarily conserved role for SoxC genes in neural crest specification and neuronal differentiation.The C. elegans SoxC protein SEM-2 opposes differentiation factors to promote a proliferative blast cell fate in the postembryonic mesoderm.Sox11 is required to maintain proper levels of Hedgehog signaling during vertebrate ocular morphogenesisKnock-down of SOX11 induces autotaxin-dependent increase in proliferation in vitro and more aggressive tumors in vivo.Antitumor activity of (R,R')-4-methoxy-1-naphthylfenoterol in a rat C6 glioma xenograft model in the mousePrognostic significance of Sox4 expression in human cutaneous melanoma and its role in cell migration and invasion.Mutation of murine Sox4 untranslated regions results in partially penetrant perinatal lethality.Pax6 regulates gene expression in the vertebrate lens through miR-204Microarray analysis of XOPS-mCFP zebrafish retina identifies genes associated with rod photoreceptor degeneration and regeneration.sox4 and sox11 function during Xenopus laevis eye developmentOverexpression of Sox11 promotes corticospinal tract regeneration after spinal injury while interfering with functional recoverySox4 regulates choroid fissure closure by limiting Hedgehog signaling during ocular morphogenesis.Keeping an eye on SOXC proteins.DNA methylation and histone modifications regulate SOX11 expression in lymphoid and solid cancer cells.Hepatitis B virus replication and sex-determining region Y box 4 production are tightly controlled by a novel positive feedback mechanism.Aryl hydrocarbon receptor agonists induce microRNA-335 expression and inhibit lung metastasis of estrogen receptor negative breast cancer cells.The transcription factor Sox11 promotes nerve regeneration through activation of the regeneration-associated gene Sprr1a.Sox11 modulates brain-derived neurotrophic factor expression in an exon promoter-specific manner.Sox11 Reduces Caspase-6 Cleavage and Activity.MiR-133a suppresses the migration and invasion of esophageal cancer cells by targeting the EMT regulator SOX4.Genomic analysis reveals distinct mechanisms and functional classes of SOX10-regulated genes in melanocytes.SOX4 contributes to the progression of cervical cancer and the resistance to the chemotherapeutic drug through ABCG2Epigenetic inactivation of the MIR129-2 in hematological malignancies.SOXC Genes and the Control of Skeletogenesis.PML-RARα co-operates with Sox4 in acute myeloid leukemia development in miceSox11 expression in astrocytic gliomas: correlation with nestin/c-Met/IDH1-R132H expression phenotypes, p-Stat-3 and survivalEpigenetic regulation of Sox4 during palate development.Small RNAs derived from lncRNA RNase MRP have gene-silencing activity relevant to human cartilage-hair hypoplasia.Epigenetic regulation of neurogenesis in the adult hippocampus.SOX11 expression in mantle cell lymphoma.Indolent mantle cell lymphoma.SOX12 and NRSN2 are candidate genes for 20p13 subtelomeric deletions associated with developmental delay.SOX4 is a potential prognostic factor in human cancers: a systematic review and meta-analysis.SOX4 induces tumor invasion by targeting EMT-related pathway in prostate cancer.SOX1 inhibits breast cancer cell growth and invasion through suppressing the Wnt/β-catenin signaling pathway.
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Critical roles for SoxC transcription factors in development and cancer.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Critical roles for SoxC transcription factors in development and cancer.
@en
Critical roles for SoxC transcription factors in development and cancer.
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type
label
Critical roles for SoxC transcription factors in development and cancer.
@en
Critical roles for SoxC transcription factors in development and cancer.
@nl
prefLabel
Critical roles for SoxC transcription factors in development and cancer.
@en
Critical roles for SoxC transcription factors in development and cancer.
@nl
P2860
P1476
Critical roles for SoxC transcription factors in development and cancer.
@en
P2093
Alfredo I Penzo-Méndez
P2860
P304
P356
10.1016/J.BIOCEL.2009.07.018
P577
2009-08-03T00:00:00Z