A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.
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Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette ConsumptionCYP2B6 non-coding variation associated with smoking cessation is also associated with differences in allelic expression, splicing, and nicotine metabolism independent of common amino-acid changesPhase II trial of S-1 plus leucovorin in patients with advanced gastric cancer and clinical prediction by S-1 pharmacogenetic pathwayGenetic determinants of CYP2A6 activity across racial/ethnic groups with different risks of lung cancer and effect on their smoking intensityVariants in two adjacent genes, EGLN2 and CYP2A6, influence smoking behavior related to disease risk via different mechanisms.The contribution of common UGT2B10 and CYP2A6 alleles to variation in nicotine glucuronidation among European AmericansNovel CYP2A6 variants identified in African Americans are associated with slow nicotine metabolism in vitro and in vivo.CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study.Genetic determinants of cytochrome P450 2A6 activity and biomarkers of tobacco smoke exposure in relation to risk of lung cancer development in the Shanghai cohort study.Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain.
P2860
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P2860
A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.
@en
A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.
@nl
type
label
A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.
@en
A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.
@nl
prefLabel
A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.
@en
A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.
@nl
P2093
P2860
P1476
A compensatory effect upon splicing results in normal function of the CYP2A6*14 allele.
@en
P2093
A Joseph Bloom
Maribel Martinez
Oscar Harari
Sandra A McDonald
Sharon E Murphy
Xiaochun Zhang
P2860
P304
P356
10.1097/FPC.0B013E32835CAF7D
P50
P577
2013-03-01T00:00:00Z