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Insulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection PathwaysMetformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent mannersBasic and clinical significance of IGF-I-induced signatures in cancerSynthesis of aryl-heteroaryl ureas (AHUs) based on 4-aminoquinoline and their evaluation against the insulin-like growth factor receptor (IGF-1R).Identification of BRCA1 As a Potential Biomarker for Insulin-Like Growth Factor-1 Receptor Targeted Therapy in Breast Cancer.Retracted: Involvement of insulin-like growth factor-1 in chemotherapy-related cognitive impairment.Thyroid diseases in patients with acromegaly.The p53 network: cellular and systemic DNA damage responses in aging and cancer.Generation and screening of monoclonal antibodies for immunoPET imaging of IGF1R in prostate cancer.Insulin-like growth factor-1 receptor and phosphorylated AKT-serine 473 expression in 132 resected thymomas and thymic carcinomasRoles for growth factors in cancer progression.Insulin-like growth factor system and sporadic malignant melanoma.Genomic and molecular characterization of malignant peripheral nerve sheath tumor identifies the IGF1R pathway as a primary target for treatment.Insulin-like growth factor-I receptor (IGF-IR) translocates to nucleus and autoregulates IGF-IR gene expression in breast cancer cells.Novel therapeutic approaches for small cell lung cancer: the future has arrivedInsights into the beneficial effect of caloric/ dietary restriction for a healthy and prolonged life.Effect of proline rich 15-deficiency on trophoblast viability and survival.Molecular imaging of insulin-like growth factor 1 receptor in cancer.IGF-I and IGFBP-3 before and after inpatient alcohol detoxification in alcohol-dependent subjects.Preclinical and first-in-human phase I studies of KW-2450, an oral tyrosine kinase inhibitor with insulin-like growth factor receptor-1/insulin receptor selectivityEphA4-deleted microenvironment regulates cancer development and leukemoid reaction of the isografted 4T1 murine breast cancer via reduction of an IGF1 signal.Insulin-like growth factor: current concepts and new developments in cancer therapy.Obesity, hyperinsulinemia and breast cancer: novel targets and a novel role for metformin.Radioimmunotherapy of solid tumors: searching for the right target.Targeting IGF-1 signaling pathways in gynecologic malignancies.[99mTc(CO)3]+-(HE)3-ZIGF1R:4551, a new Affibody conjugate for visualization of insulin-like growth factor-1 receptor expression in malignant tumours.Cell surface receptor expression patterns in osteosarcoma.IGF-I enhances α5β1 integrin expression and cell motility in human chondrosarcoma cells.Insulin-IGF signaling affects cell transformation in the BALB/c 3T3 cell model.GH, IGF-1, and Age Are Important Contributors to Thyroid Abnormalities in Patients with Acromegaly.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeting the IGF1 axis in cancer proliferation.
@en
Targeting the IGF1 axis in cancer proliferation.
@nl
type
label
Targeting the IGF1 axis in cancer proliferation.
@en
Targeting the IGF1 axis in cancer proliferation.
@nl
prefLabel
Targeting the IGF1 axis in cancer proliferation.
@en
Targeting the IGF1 axis in cancer proliferation.
@nl
P2093
P2860
P1476
Targeting the IGF1 axis in cancer proliferation.
@en
P2093
Haim Werner
Ilan Bruchim
Zohar Attias
P2860
P304
P356
10.1517/14728220903201702
P407
P577
2009-10-01T00:00:00Z