Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
about
GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.Loss of Hepatic Mitochondrial Long-Chain Fatty Acid Oxidation Confers Resistance to Diet-Induced Obesity and Glucose Intolerance.Muscle Directs Diurnal Energy Homeostasis through a Myokine-Dependent Hormone Module in Drosophila.Mitochondrial dysfunction in cancer: Potential roles of ATF5 and the mitochondrial UPR.Antihypertrophic Effects of Small Molecules that Maintain Mitochondrial ATP Levels Under Hypoxia.The mitochondrial UPR: mechanisms, physiological functions and implications in ageing.GDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury.Growth differentiation factor 15 predicts advanced fibrosis in biopsy-proven non-alcoholic fatty liver disease.Mitochondrial retrograde signaling in the nervous system.Exercise increases circulating GDF15 in humans.Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver.Reduced oxidative capacity in macrophages results in systemic insulin resistance.Inhibition of the ER stress IRE1α inflammatory pathway protects against cell death in mitochondrial complex I mutant cells.The mitochondrial unfolded protein response and mitohormesis: a perspective on metabolic diseasesPerturbed Redox Signaling Exacerbates a Mitochondrial MyopathyPathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic Approaches
P2860
Q38605928-CB562CD7-3DE2-4989-8880-3D23ECCAD399Q38672086-4E260400-2694-495F-97F0-C8AD6E92ED06Q38697788-C06BF071-7919-4F2C-AD84-46A577B2CC01Q39303215-CD47EC9A-247E-488F-A176-F78CCA0C50CCQ42651346-838FA17A-8315-407F-ADD0-713F5512F9CEQ46256193-2207E961-B289-40BC-9FC7-345C87A84800Q47104373-EBBA706E-BBDC-4AA2-A32E-B99C3BF6C4D4Q47684686-1D74735E-7613-4289-8667-C10CB469F229Q48098220-0D9EA9D3-7D79-46D3-84C6-3D62FFB2FFE1Q49339915-F726A805-6BD4-4EE1-8605-DB2F6209DC4DQ51246528-1A24E1B7-F6A8-4964-B138-7C9338DC5199Q53693528-BD536EC2-FD35-4912-93A3-59C51E78F378Q54977435-9A1841F1-6C46-4D2E-853C-0F264497B473Q57299043-BB833246-6376-4F32-8FC6-79D79E1FDDD8Q58696816-BF0676CF-56AE-435E-A286-524CF02EC5D9Q58705640-72BB3476-B85F-4679-BFF0-3A92D1A62CC2
P2860
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 December 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
@ast
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
@en
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
@nl
type
label
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
@ast
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
@en
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
@nl
prefLabel
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
@ast
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
@en
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.
@nl
P2093
P2860
P50
P356
P1476
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis
@en
P2093
Gi Ryang Kweon
Joon Young Chang
Jung Hwan Hwang
Michael Downes
Min Jeong Choi
Min Jeong Ryu
Seong Eun Lee
Soung Jung Kim
P2860
P304
P356
10.1083/JCB.201607110
P407
P50
P577
2016-12-16T00:00:00Z