Tetrahydrobiopterin, a cofactor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine.
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Human GTP cyclohydrolase I: only one out of three cDNA isoforms gives rise to the active enzymeNitric oxide synthases in mammalsTetrahydrobiopterin biosynthesis, regeneration and functionsNitric oxide synthases: structure, function and inhibitionStimulation of human nitric oxide synthase by tetrahydrobiopterin and selective binding of the cofactorContrasting effects of N5-substituted tetrahydrobiopterin derivatives on phenylalanine hydroxylase, dihydropteridine reductase and nitric oxide synthaseTyrosine HydroxylaseTetrahydrobiopterin in cardiovascular health and disease.Expression of human inducible nitric oxide synthase in a tetrahydrobiopterin (H4B)-deficient cell line: H4B promotes assembly of enzyme subunits into an active dimerRegulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity.Tetrahydrobiopterin restores diastolic function and attenuates superoxide production in ovariectomized mRen2.Lewis ratsNO., CO and .OH. Endogenous soluble guanylyl cyclase-activating factors.Effects of transition metals on nitric oxide synthase catalysisNo .NO from NO synthase.Purification of a distinctive form of endotoxin-induced nitric oxide synthase from rat liver.Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease.Tetrahydrobiopterin in nitric oxide synthase.Catalytic reduction of a tetrahydrobiopterin radical within nitric-oxide synthase.Immunobiology of Nitric Oxide and Regulation of Inducible Nitric Oxide Synthase.Nitric oxide/cyclic GMP-mediated signal transduction.Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer.Allosteric regulation of neuronal nitric oxide synthase by tetrahydrobiopterin and suppression of auto-damaging superoxide.Reactivity of tetrahydrobiopterin bound to nitric-oxide synthase.Coexpression of GTP cyclohydrolase I and inducible nitric oxide synthase mRNAs in mouse osteoblastic cells activated by proinflammatory cytokines.Reduction of quinonoid dihydrobiopterin to tetrahydrobiopterin by nitric oxide synthase.Characteristics of the nitric oxide synthase-catalyzed conversion of arginine to N-hydroxyarginine, the first oxygenation step in the enzymic synthesis of nitric oxide.NO accounts completely for the oxygenated nitrogen species generated by enzymic L-arginine oxygenation.Synthesis and characterization of 3H-labelled tetrahydrobiopterin.Identification of the 4-amino analogue of tetrahydrobiopterin as a dihydropteridine reductase inhibitor and a potent pteridine antagonist of rat neuronal nitric oxide synthase.Identification and characterization of a calmodulin-dependent nitric oxide synthase from GH3 pituitary cells.Subcellular localization and characterization of nitric oxide synthase(s) in endothelial cells: physiological implications.Tetrahydrobiopterin cofactor biosynthesis: GTP cyclohydrolase I mRNA expression in rat brain and superior cervical ganglia.Anti-pterins as tools to characterize the function of tetrahydrobiopterin in NO synthase.Dexamethasone suppresses iNOS yet induces GTPCH and CAT-2 mRNA expression in rat lungs.Localization of GTP cyclohydrolase in monoaminergic but not nitric oxide-producing cells.Tetrahydrobiopterin redox cycling in nitric oxide synthase: evidence supports a through-heme electron delivery.Modulation of the remote heme site geometry of recombinant mouse neuronal nitric-oxide synthase by the N-terminal hook region.
P2860
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P2860
Tetrahydrobiopterin, a cofactor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Tetrahydrobiopterin, a cofacto ...... n the oxygenation of arginine.
@en
Tetrahydrobiopterin, a cofacto ...... n the oxygenation of arginine.
@nl
type
label
Tetrahydrobiopterin, a cofacto ...... n the oxygenation of arginine.
@en
Tetrahydrobiopterin, a cofacto ...... n the oxygenation of arginine.
@nl
prefLabel
Tetrahydrobiopterin, a cofacto ...... n the oxygenation of arginine.
@en
Tetrahydrobiopterin, a cofacto ...... n the oxygenation of arginine.
@nl
P2093
P2860
P356
P1476
Tetrahydrobiopterin, a cofacto ...... n the oxygenation of arginine.
@en
P2093
Giovanelli J
P2860
P304
P356
10.1073/PNAS.88.16.7091
P407
P577
1991-08-01T00:00:00Z