Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells
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Mammalian mitochondrial and cytosolic folylpolyglutamate synthetase maintain the subcellular compartmentalization of folatesMathematical models of cancer metabolismMYC, Metabolism, and CancerSerine and glycine metabolism in cancerRedox control of glutamine utilization in cancerInsulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1Imaging tumor metabolism using positron emission tomographyNeu-Laxova syndrome is a heterogeneous metabolic disorder caused by defects in enzymes of the L-serine biosynthesis pathwayReconstruction of Tissue-Specific Metabolic Networks Using CORDAThe Intercellular Metabolic Interplay between Tumor and Immune CellsMetabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancerEarly Detection of Treatment-Induced Mitotic Arrest Using Temporal Diffusion Magnetic Resonance Spectroscopy.Submolecular regulation of cell transformation by deuterium depleting water exchange reactions in the tricarboxylic acid substrate cycle.Quantitative Evaluation of the Compatibility Effects of Huangqin Decoction on the Treatment of Irinotecan-Induced Gastrointestinal Toxicity Using Untargeted MetabolomicsOne-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy.Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome.iNOS-derived nitric oxide promotes glycolysis by inducing pyruvate kinase M2 nuclear translocation in ovarian cancerThe early metabolomic response of adipose tissue during acute cold exposure in mice.Quantitative flux analysis reveals folate-dependent NADPH production.Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cellsMetabolic effect of TAp63α: enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defenseTAp73 promotes anti-senescence-anabolism not proliferation.Bioinformatics analysis of the serine and glycine pathway in cancer cellsCharacterization of the usage of the serine metabolic network in human cancerOVCAR-3 spheroid-derived cells display distinct metabolic profilesTAp73 promotes anabolismcMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.Quantification of folate metabolism using transient metabolic flux analysis.Fructose Alters Intermediary Metabolism of Glucose in Human Adipocytes and Diverts Glucose to Serine Oxidation in the One-Carbon Cycle Energy Producing Pathway.HSPA12B: a novel facilitator of lung tumor growthArginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthaseMolecular imaging of folate receptor β-positive macrophages during acute lung inflammation.Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) and serine biosynthetic pathway genes are co-ordinately increased during anabolic agent-induced skeletal muscle growth.Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity.Metabolic Reprogramming and Dependencies Associated with Epithelial Cancer Stem Cells Independent of the Epithelial-Mesenchymal Transition Program.Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation.Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer.The Pasteur's Dictum: Nitrogen Promotes Growth and Oxygen Reduces the Need for Sugar.Regulation of mammalian nucleotide metabolism and biosynthesisMetabolic rewiring of pancreatic ductal adenocarcinoma: New routes to follow within the maze.
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Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Contribution of serine, folate ...... e requirements of cancer cells
@en
Contribution of serine, folate ...... requirements of cancer cells.
@nl
type
label
Contribution of serine, folate ...... e requirements of cancer cells
@en
Contribution of serine, folate ...... requirements of cancer cells.
@nl
prefLabel
Contribution of serine, folate ...... e requirements of cancer cells
@en
Contribution of serine, folate ...... requirements of cancer cells.
@nl
P2093
P2860
P356
P1476
Contribution of serine, folate ...... e requirements of cancer cells
@en
P2093
D Dvorzhinski
E K Markert
J R Bertino
K M Hirshfield
L L-Y Chan
P2860
P356
10.1038/CDDIS.2013.393
P577
2013-10-24T00:00:00Z