Inhibition of canonical WNT/β-catenin signaling is involved in leflunomide (LEF)-mediated cytotoxic effects on renal carcinoma cells.
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Reduced E-cadherin facilitates renal cell carcinoma progression by WNT/β-catenin signaling activation.Inhibition of p70 S6 kinase (S6K1) activity by A77 1726, the active metabolite of leflunomide, induces autophagy through TAK1-mediated AMPK and JNK activation.Wnt-signaling enhances neural crest migration of melanoma cells and induces an invasive phenotype.Inhibition of p70 S6 kinase activity by A77 1726 induces autophagy and enhances the degradation of superoxide dismutase 1 (SOD1) protein aggregates.
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Inhibition of canonical WNT/β-catenin signaling is involved in leflunomide (LEF)-mediated cytotoxic effects on renal carcinoma cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 July 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Inhibition of canonical WNT/β- ...... ects on renal carcinoma cells.
@en
Inhibition of canonical WNT/β-catenin signaling is involved in leflunomide
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type
label
Inhibition of canonical WNT/β- ...... ects on renal carcinoma cells.
@en
Inhibition of canonical WNT/β-catenin signaling is involved in leflunomide
@nl
prefLabel
Inhibition of canonical WNT/β- ...... ects on renal carcinoma cells.
@en
Inhibition of canonical WNT/β-catenin signaling is involved in leflunomide
@nl
P2093
P2860
P356
P1433
P1476
Inhibition of canonical WNT/β- ...... ects on renal carcinoma cells.
@en
P2093
P2860
P304
50401-50416
P356
10.18632/ONCOTARGET.10409
P407
P577
2016-07-06T00:00:00Z