Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation.
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Complex mechanisms linking neurocognitive dysfunction to insulin resistance and other metabolic dysfunctionNovel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver HomeostasisMechanistic target of rapamycin (mTOR): a point of convergence in the action of insulin/IGF-1 and G protein-coupled receptor agonists in pancreatic cancer cellsTreatment of nonalcoholic steatohepatitis in adults: present and futureImplication of inflammatory signaling pathways in obesity-induced insulin resistanceJudicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and PerspectivesRegulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2Insulin induces REDD1 expression through hypoxia-inducible factor 1 activation in adipocytesCaffeine modulates phosphorylation of insulin receptor substrate-1 and impairs insulin signal transduction in rat skeletal muscleTpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis.Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain.Pathogenesis of insulin resistance in skeletal muscle.Involvement of receptor-interacting protein 140 in palmitate-stimulated macrophage infiltration of pancreatic beta cells.Regulation of basal cellular physiology by the homeostatic unfolded protein responseChronic unpredictable stress regulates visceral adipocyte-mediated glucose metabolism and inflammatory circuits in male rats.Translational approaches: from fatty liver to non-alcoholic steatohepatitis.cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistanceTroglitazone induces cytotoxicity in part by promoting the degradation of peroxisome proliferator-activated receptor γ co-activator-1α protein.Hepatic mitogen-activated protein kinase phosphatase 1 selectively regulates glucose metabolism and energy homeostasis.Suppression of feedback loops mediated by PI3K/mTOR induces multiple overactivation of compensatory pathways: an unintended consequence leading to drug resistance.Regulated in development and DNA damage responses -1 (REDD1) protein contributes to insulin signaling pathway in adipocytes.Erythropoietin inhibits gluconeogenesis and inflammation in the liver and improves glucose intolerance in high-fat diet-fed mice.Insulin resistance in Alzheimer's disease.Diabetes mellitus: The epidemic of the century.Computational modelling of the regulation of Insulin signalling by oxidative stress.Non-steroidal anti-inflammatory drugs activate NADPH oxidase in adipocytes and raise the H2O2 pool to prevent cAMP-stimulated protein kinase a activation and inhibit lipolysisInsulin receptor substrate 2 expression and involvement in neuronal insulin resistance in diabetic neuropathyMAP3K8 (TPL2/COT) affects obesity-induced adipose tissue inflammation without systemic effects in humans and in mice.5'-AMP-activated protein kinase increases glucose uptake independent of GLUT4 translocation in cardiac myocytes.Profiles of serum amino acids to screen for catabolic and inflammation status in calves with Mycoplasma bronchopneumonia.Prenatal stress enhances excitatory synaptic transmission and impairs long-term potentiation in the frontal cortex of adult offspring ratsBoth ERK1 and ERK2 are required for enterovirus 71 (EV71) efficient replication.Subcutaneous adipose tissue macrophage infiltration is associated with hepatic and visceral fat deposition, hyperinsulinemia, and stimulation of NF-κB stress pathway.Elevated NF-κB activation is conserved in human myocytes cultured from obese type 2 diabetic patients and attenuated by AMP-activated protein kinaseToll-like receptor 5 in obesity: the role of gut microbiota and adipose tissue inflammation.Role of substance P in the regulation of glucose metabolism via insulin signaling-associated pathways.Vascular smooth muscle insulin resistance, but not hypertrophic signaling, is independent of angiotensin II-induced IRS-1 phosphorylation by JNKReproductive tissues maintain insulin sensitivity in diet-induced obesity.Consequences of Aberrant Insulin Regulation in the Brain: Can Treating Diabetes be Effective for Alzheimer's Disease.Insulin signaling in retinal neurons is regulated within cholesterol-enriched membrane microdomains.
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Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cellular mechanisms of insulin ...... (IRS) serine phosphorylation.
@en
Cellular mechanisms of insulin ...... nd insulin receptor substrates
@nl
type
label
Cellular mechanisms of insulin ...... (IRS) serine phosphorylation.
@en
Cellular mechanisms of insulin ...... nd insulin receptor substrates
@nl
prefLabel
Cellular mechanisms of insulin ...... (IRS) serine phosphorylation.
@en
Cellular mechanisms of insulin ...... nd insulin receptor substrates
@nl
P1476
Cellular mechanisms of insulin ...... (IRS) serine phosphorylation.
@en
P2093
Jean-François Tanti
Jennifer Jager
P304
P356
10.1016/J.COPH.2009.07.004
P577
2009-08-13T00:00:00Z