HSP90 inhibitors: multi-targeted antitumor effects and novel combinatorial therapeutic approaches in cancer therapy.
about
Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienaymé reaction and their Hsp90 inhibitory activityProtein folding in the cytoplasm and the heat shock response.Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers.Retinoblastoma protein modulates the inverse relationship between cellular proliferation and elastogenesisMechanisms of Trastuzumab resistance in ErbB2-driven breast cancer and newer opportunities to overcome therapy resistance.Attenuated oncolytic measles virus strains as cancer therapeuticsPotent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression.Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli.HSP90 manages the ends.MR evaluation of response to targeted treatment in cancer cells.The heat shock protein 90 inhibitor SNX5422 has a synergistic activity with histone deacetylase inhibitors in induction of death of anaplastic thyroid carcinoma cells.Pharmacologic heat shock protein 70 induction confers cytoprotection against inflammation in gliovascular cells.Identification of potential pathways involved in the induction of cell cycle arrest and apoptosis by a new 4-arylidene curcumin analogue T63 in lung cancer cells: a comparative proteomic analysis.Licochalcone A enhances geldanamycin-induced apoptosis through reactive oxygen species-mediated caspase activation.18β-glycyrrhetinic acid potentiates Hsp90 inhibition-induced apoptosis in human epithelial ovarian carcinoma cells via activation of death receptor and mitochondrial pathway.Combined effect of Hsp90 inhibitor geldanamycin and parthenolide via reactive oxygen species-mediated apoptotic process on epithelial ovarian cancer cells.Radicicol, an inhibitor of Hsp90, enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells by promoting activation of apoptosis-related proteins.High-level expression of Hsp90β is associated with poor survival in resectable non-small-cell lung cancer patients.
P2860
Q27696798-0D2A16C8-068C-4899-B829-E777F60DD90BQ34152827-CF62871A-766E-4376-88EF-002563D62986Q34616517-881687C5-3D98-48FC-A463-12650131F755Q35378176-D7736639-6EEE-461E-A1DF-EF4F70E3C576Q35624814-1647592E-0B49-431D-994B-0886C683FEB3Q35818876-37ADBBDF-442B-42B1-8E11-418E4A724A4AQ36642876-2FE1D975-B6EA-474C-B113-C3B0970A9152Q37138626-30586330-607E-4A7D-950A-79DD3E3282CEQ37710830-BE408F23-7EFC-442A-9A13-9357AD0147F1Q37851076-59C0673B-8E56-4121-A3EC-BB817EC37207Q38848546-9660B6EC-7D77-4414-A0A8-8F47123EE3F9Q38895909-2E0C7AA6-AFAD-4FB5-9052-6ABBCE3DD88EQ39013461-4A80CCDA-07FB-4735-A5C9-9A5AD9109415Q39114307-9FD4CEB2-AC00-4A36-BA64-CCE46ED8D5D5Q39302074-F8DAD60C-3BD4-4F42-8C20-E88A63E55512Q39376431-C65278B6-8E3D-4C65-94B2-B07CE176FE0AQ39498655-161A7450-953D-434F-BC30-369E3A29E3C1Q48222968-910A97AC-39D8-4D82-B372-FE8C2F618178
P2860
HSP90 inhibitors: multi-targeted antitumor effects and novel combinatorial therapeutic approaches in cancer therapy.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
HSP90 inhibitors: multi-target ...... approaches in cancer therapy.
@en
HSP90 inhibitors: multi-target ...... approaches in cancer therapy.
@nl
type
label
HSP90 inhibitors: multi-target ...... approaches in cancer therapy.
@en
HSP90 inhibitors: multi-target ...... approaches in cancer therapy.
@nl
prefLabel
HSP90 inhibitors: multi-target ...... approaches in cancer therapy.
@en
HSP90 inhibitors: multi-target ...... approaches in cancer therapy.
@nl
P2093
P1476
HSP90 inhibitors: multi-target ...... approaches in cancer therapy.
@en
P2093
P304
P356
10.2174/092986709788802999
P577
2009-01-01T00:00:00Z