Population pharmacokinetic modeling and dosing simulations of nitrogen-scavenging compounds: disposition of glycerol phenylbutyrate and sodium phenylbutyrate in adult and pediatric patients with urea cycle disorders
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Averting the foul taste of pediatric medicines improves adherence and can be lifesaving - Pheburane® (sodium phenylbutyrate)Strategies to rescue the consequences of inducible arginase-1 deficiency in miceSwitch from Sodium Phenylbutyrate to Glycerol Phenylbutyrate Improved Metabolic Stability in an Adolescent with Ornithine Transcarbamylase DeficiencyUrinary phenylacetylglutamine (U-PAGN) concentration as biomarker for adherence in patients with urea cycle disorders (UCD) treated with glycerol phenylbutyrate.Elevated phenylacetic acid levels do not correlate with adverse events in patients with urea cycle disorders or hepatic encephalopathy and can be predicted based on the plasma PAA to PAGN ratio.Glycerol phenylbutyrate treatment in children with urea cycle disorders: pooled analysis of short and long-term ammonia control and outcomes.4-Phenylbutyric Acid Attenuates Pancreatic Beta-Cell Injury in Rats with Experimental Severe Acute Pancreatitis.The unfolded protein response impacts melanoma progression by enhancing FGF expression and can be antagonized by a chemical chaperone.
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P2860
Population pharmacokinetic modeling and dosing simulations of nitrogen-scavenging compounds: disposition of glycerol phenylbutyrate and sodium phenylbutyrate in adult and pediatric patients with urea cycle disorders
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 June 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Population pharmacokinetic mod ...... ents with urea cycle disorders
@en
Population pharmacokinetic mod ...... nts with urea cycle disorders.
@nl
type
label
Population pharmacokinetic mod ...... ents with urea cycle disorders
@en
Population pharmacokinetic mod ...... nts with urea cycle disorders.
@nl
prefLabel
Population pharmacokinetic mod ...... ents with urea cycle disorders
@en
Population pharmacokinetic mod ...... nts with urea cycle disorders.
@nl
P2093
P2860
P356
P1476
Population pharmacokinetic mod ...... ents with urea cycle disorders
@en
P2093
B F Scharschmidt
Jon P R Monteleone
K Dickinson
M Mokhtarani
U Lichter-Konecki
P2860
P304
P356
10.1002/JCPH.92
P577
2013-06-15T00:00:00Z