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HYAL-2-WWOX-SMAD4 Signaling in Cell Death and Anticancer ResponsePleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer CellsA genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303Genome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk.WWOX gene is associated with HDL cholesterol and triglyceride levels.WWOX suppresses KLF5 expression and breast cancer cell growthWWOX, the common fragile site FRA16D gene product, regulates ATM activation and the DNA damage response.Common fragile site tumor suppressor genes and corresponding mouse models of cancer.Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression.HIF-1α confers aggressive malignant traits on human tumor cells independent of its canonical transcriptional functionThe WWOX gene modulates high-density lipoprotein and lipid metabolism.Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.Ectopic expression of the WWOX gene suppresses stemness of human ovarian cancer stem cells.Identification of an In Vivo MEK/WOX1 Complex as a Master Switch for Apoptosis in T Cell Leukemia.Structural insights into the functional versatility of WW domain-containing oxidoreductase tumor suppressor.Allostery mediates ligand binding to WWOX tumor suppressor via a conformational switch.Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain.Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo.A multi-exon deletion within WWOX is associated with a 46,XY disorder of sex developmentBiophysical basis of the binding of WWOX tumor suppressor to WBP1 and WBP2 adaptorsA multistage genetic association study identifies breast cancer risk loci at 10q25 and 16q24Role of WW domain proteins WWOX in development, prognosis, and treatment response of glioma.Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductaseModulation of Sonic hedgehog signaling and WW domain containing oxidoreductase WOX1 expression enhances radiosensitivity of human glioblastoma cells.WWOX dysfunction induces sequential aggregation of TRAPPC6AΔ, TIAF1, tau and amyloid β, and causes apoptosis.Effects of 5-Aza-2'-deoxycytidine on the methylation state and function of the WWOX gene in the HO-8910 ovarian cancer cell linePDLIM2 regulates transcription factor activity in epithelial-to-mesenchymal transition via the COP9 signalosome.Molecular origin of the binding of WWOX tumor suppressor to ErbB4 receptor tyrosine kinase.The supposed tumor suppressor gene WWOX is mutated in an early lethal microcephaly syndrome with epilepsy, growth retardation and retinal degeneration.Conditional inactivation of the mouse Wwox tumor suppressor gene recapitulates the null phenotype.Oncogenic roles of the SETDB2 histone methyltransferase in gastric cancer.WWOX gene and gene product: tumor suppression through specific protein interactions.Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase.WW domain interactions regulate the Hippo tumor suppressor pathway.Role of the WWOX tumor suppressor gene in bone homeostasis and the pathogenesis of osteosarcoma.WW domain-containing oxidoreductase's role in myriad cancers: clinical significance and future implications.The common fragile site FRA16D gene product WWOX: roles in tumor suppression and genomic stability.The tumor suppressor WW domain-containing oxidoreductase modulates cell metabolism.WWOX: a fragile tumor suppressor.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
WWOX: its genomics, partners, and functions.
@en
WWOX: its genomics, partners, and functions.
@nl
type
label
WWOX: its genomics, partners, and functions.
@en
WWOX: its genomics, partners, and functions.
@nl
prefLabel
WWOX: its genomics, partners, and functions.
@en
WWOX: its genomics, partners, and functions.
@nl
P2093
P356
P1476
WWOX: its genomics, partners, and functions.
@en
P2093
Rami I Aqeilan
Sara Del Mare
Zaidoun Salah
P304
P356
10.1002/JCB.22298
P577
2009-11-01T00:00:00Z