Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line.
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Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?Ribonucleoside Analogue That Blocks Replication of Bovine Viral Diarrhea and Hepatitis C Viruses in CultureSynergistic In Vitro Interactions between Alpha Interferon and Ribavirin against Bovine Viral Diarrhea Virus and Yellow Fever Virus as Surrogate Models of Hepatitis C Virus ReplicationNovel pyrazolo[3,4-d]pyrimidine nucleoside analog with broad-spectrum antiviral activityEffects of Mutagenic and Chain-Terminating Nucleotide Analogs on Enzymes Isolated from Hepatitis C Virus Strains of Various GenotypesThe Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug DesignComparative inhibition of influenza and parainfluenza virus replication by ribavirin in MDCK cellsThe antiherpesvirus activity of H2G [(R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine] is markedly enhanced by the novel immunosuppressive agent mycophenolate mofetil.The synthesis and antiviral activity of 4-fluoro-1-beta-D-ribofuranosyl-1H-pyrazole-3-carboxamideCell type mediated resistance of vesicular stomatitis virus and Sendai virus to ribavirinOverexpression, purification and crystallographic analysis of a unique adenosine kinase from Mycobacterium tuberculosisNovel Characteristics of Trypanosoma brucei Guanosine 5'-monophosphate Reductase Distinct from Host AnimalsSensitive radioimmunoassay for the broad-spectrum antiviral agent ribavirinHeberden oration 1979: human aberrations of purine metabolism and their significance for rheumatology.Human purine metabolism: some recent advances and relationships with immunodeficiencyMechanisms of action of ribavirin in antiviral therapies.Population pharmacokinetic modeling of plasma and intracellular ribavirin concentrations in patients with chronic hepatitis C virus infectionMetabolism of ribavirin in respiratory syncytial virus-infected and uninfected cells.Nucleoside kinases in T and B lymphoblasts distinguished by autoradiography.Selective inhibition of functional lymphocyte subpopulations by ribavirin.Resistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation.Investigating the Influence of Ribavirin on Human Respiratory Syncytial Virus RNA Synthesis by Using a High-Resolution Transcriptome Sequencing Approach.The role of the equilibrative nucleoside transporter 1 (ENT1) in transport and metabolism of ribavirin by human and wild-type or Ent1-/- mouse erythrocytes.The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.Biochemistry and clinical applications of ribavirin.Activation and deactivation of a broad-spectrum antiviral drug by a single enzyme: adenosine deaminase catalyzes two consecutive deamination reactionsHomologous interference of lymphocytic choriomeningitis virus involves a ribavirin-susceptible block in virus replication.Identification of a nucleoside analog active against adenosine kinase-expressing plasma cell malignancies.Pharmacogenetics of ribavirin-induced anemia in HCV patients.Disposition and metabolic profiles of [14C]viramidine and [14C]ribavirin in rat and monkey red blood cells and liver.Host-directed Inhibitors of Myxoviruses: Synthesis and in vitro Biochemical Evaluation.Assay method for monitoring the inhibitory effects of antimetabolites on the activity of inosinate dehydrogenase in intact human CEM lymphocytesAsymmetric synthesis of host-directed inhibitors of myxoviruses.Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5'-triphosphate, not with inhibition of IMP dehydrogenase.Phosphorylation of ribavirin and viramidine by adenosine kinase and cytosolic 5'-nucleotidase II: Implications for ribavirin metabolism in erythrocytes.Modeling the antiviral activity of ribavirin against hepatitis C virus in cell culture.Investigation of hyperuricemia during pegylated-interferon-alpha2b plus ribavirin combination therapy in patients with chronic hepatitis C.Implications of a circular dichroism and theoretical investigation of ribavirin-related derivatives in drug design.
P2860
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P2860
Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1978
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Adenosine kinase initiates the ...... in a cultured human cell line.
@en
Adenosine kinase initiates the ...... in a cultured human cell line.
@nl
type
label
Adenosine kinase initiates the ...... in a cultured human cell line.
@en
Adenosine kinase initiates the ...... in a cultured human cell line.
@nl
prefLabel
Adenosine kinase initiates the ...... in a cultured human cell line.
@en
Adenosine kinase initiates the ...... in a cultured human cell line.
@nl
P2093
P2860
P356
P1476
Adenosine kinase initiates the ...... in a cultured human cell line.
@en
P2093
Seegmiller JE
P2860
P304
P356
10.1073/PNAS.75.7.3042
P407
P577
1978-07-01T00:00:00Z