Cks1: Structure, Emerging Roles and Implications in Multiple Cancers
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The basal transcription machinery as a target for cancer therapyAsparaginase treatment side-effects may be due to genes with homopolymeric Asn codons (Review-Hypothesis)TORC1 coordinates the conversion of Sic1 from a target to an inhibitor of cyclin-CDK-Cks1.Hypoxia drives transient site-specific copy gain and drug-resistant gene expression.Gene signature associated with benign neurofibroma transformation to malignant peripheral nerve sheath tumorsRegulation of Transient Site-specific Copy Gain by MicroRNA.TGF-β activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.Increased expression of Cks1 protein is associated with lymph node metastasis and poor prognosis in nasopharyngeal carcinoma.Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells.The cyclin dependent kinase subunit Cks1 is required for infection-associated development of the rice blast fungus Magnaporthe oryzae.The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability.Long noncoding RNA MALAT1 affects the efficacy of radiotherapy for esophageal squamous cell carcinoma by regulating Cks1 expression.CKS1BP7, a Pseudogene of CKS1B, is Co-Amplified with IGF1R in Breast Cancers.
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Cks1: Structure, Emerging Roles and Implications in Multiple Cancers
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cks1: Structure, Emerging Roles and Implications in Multiple Cancers
@en
Cks1: Structure, Emerging Roles and Implications in Multiple Cancers.
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type
label
Cks1: Structure, Emerging Roles and Implications in Multiple Cancers
@en
Cks1: Structure, Emerging Roles and Implications in Multiple Cancers.
@nl
prefLabel
Cks1: Structure, Emerging Roles and Implications in Multiple Cancers
@en
Cks1: Structure, Emerging Roles and Implications in Multiple Cancers.
@nl
P2860
P356
P1476
Cks1: Structure, Emerging Roles and Implications in Multiple Cancers
@en
P2093
Jaideep V Thottassery
Vinayak Khattar
P2860
P304
P356
10.4236/JCT.2013.48159
P577
2013-10-01T00:00:00Z