The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosis
about
The structure of human 15-lipoxygenase-2 with a substrate mimicReactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell FormationUltrasound stimulates formation and release of vasoactive compounds in brain endothelial cellsRemoving reference mapping biases using limited or no genotype data identifies allelic differences in protein binding at disease-associated loci.Common therapeutic targets in cardiometabolic diseaseROS-dependent Syk and Pyk2-mediated STAT1 activation is required for 15(S)-hydroxyeicosatetraenoic acid-induced CD36 expression and foam cell formationEzh2-mediated repression of a transcriptional pathway upstream of Mmp9 maintains integrity of the developing vasculature.12/15-Lipoxygenase-dependent ROS production is required for diet-induced endothelial barrier dysfunction.Urotensin-II receptor stimulation of cardiac L-type Ca2+ channels requires the βγ subunits of Gi/o-protein and phosphatidylinositol 3-kinase-dependent protein kinase C β1 isoform.Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-hydroxyeicosatetraenoic acid partly via protein kinase C ε-mediated zona occludens-1 phosphorylation at threonine 770/772.Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization.Physical exercise and epigenetic adaptations of the cardiovascular system.Heterodimers of the transcriptional factors NFATc3 and FosB mediate tissue factor expression for 15(S)-hydroxyeicosatetraenoic acid-induced monocyte trafficking.CREB Negatively Regulates IGF2R Gene Expression and Downstream Pathways to Inhibit Hypoxia-Induced H9c2 Cardiomyoblast Cell Death.Upregulation of Dickkopf1 by oscillatory shear stress accelerates atherogenesis.Increased miR-223 expression in T cells from patients with rheumatoid arthritis leads to decreased insulin-like growth factor-1-mediated interleukin-10 production.Overexpression of CREB protein protects from tunicamycin-induced apoptosis in various rat cell types.Detection of atherosclerotic plaques in ApoE-deficient mice using (99m)Tc-duramycin.ROS via BTK-p300-STAT1-PPARγ signaling activation mediates cholesterol crystals-induced CD36 expression and foam cell formation.Membrane-dependent Activities of Human 15-LOX-2 and Its Murine Counterpart: IMPLICATIONS FOR MURINE MODELS OF ATHEROSCLEROSISIL-17A Enhances Microglial Response to OGD by Regulating p53 and PI3K/Akt Pathways with Involvement of ROS/HMGB1.Smooth Muscle Cell-Derived Interleukin-17C Plays an Atherogenic Role via the Recruitment of Proinflammatory Interleukin-17A+ T Cells to the Aorta.Cyclic AMP-Responsive Element-Binding Protein (CREB) is Critical in Autoimmunity by Promoting Th17 but Inhibiting Treg Cell Differentiation.Interleukin-17 alters the biology of many cell types involved in the genesis of psoriasis, systemic inflammation and associated comorbidities.
P2860
Q24329199-351EB3B2-AFB0-499C-B75E-51DBFFB5A301Q28115789-25D96A55-9A9D-45BF-9F92-3829B3ECCD32Q30376498-B6C6AEEF-9E0E-4C59-9F7A-B77F288FF2EBQ30982599-2AF2381F-1554-4C72-9096-24F6824A750AQ34251343-56276434-CCA2-4019-B2AB-F76521544B8CQ34620107-EA8D74E9-4319-4513-A037-A28491A25CC0Q34999341-CA71B2F9-92FD-4761-A53F-18F3C59C24CDQ35120907-27CD6908-7D18-4547-8A11-EA33E519B437Q35221658-234E77B2-9457-41E3-8C2E-A1631C50661BQ37563388-8DD021F8-3673-4D98-A711-9BE599E6A211Q37588413-C4614AF2-BF32-4F32-AD9A-D0738372367AQ38368200-D84CCED0-4482-4A16-B82D-506E7408E92FQ38696812-A8646F7F-DE0C-4EAB-88DE-41E8AC29FB91Q38816393-DECDD06F-A21D-4431-92B4-81CC3CAE8B04Q38816713-0C5DA8E9-191A-4067-9663-C12E472FB7F0Q38996212-0CE9A1D0-793D-4E55-B084-5C088B38F286Q39005322-9E4C3BB6-6AD0-4BB2-948A-BB6A9195414DQ39728613-E9A94347-76E3-49CD-93F4-7EE6A0ED0C2AQ40345587-8C038A10-E721-4591-BB94-B757C4497F04Q41049534-17A7B67D-35B6-4579-B74A-2E9791E14DF1Q41605512-D6AD9938-E1D4-4911-9E83-BC32CB0553C1Q42329957-B75897DB-95C7-42E3-A353-A547699A403EQ47149234-6B9931C0-1B60-48DF-9435-BED4F7821EA9Q47704613-0EB3E541-9DF1-4621-971D-58667283D094
P2860
The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosis
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 17 September 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The transcription factor CREB ...... mouse model of atherosclerosis
@en
The transcription factor CREB ...... ouse model of atherosclerosis.
@nl
type
label
The transcription factor CREB ...... mouse model of atherosclerosis
@en
The transcription factor CREB ...... ouse model of atherosclerosis.
@nl
prefLabel
The transcription factor CREB ...... mouse model of atherosclerosis
@en
The transcription factor CREB ...... ouse model of atherosclerosis.
@nl
P2093
P2860
P921
P1433
P1476
The transcription factor CREB ...... mouse model of atherosclerosis
@en
P2093
Gabor J Tigyi
Gadiparthi N Rao
Mark R Heckle
Nikhlesh K Singh
P2860
P356
10.1126/SCISIGNAL.2004214
P577
2013-09-17T00:00:00Z