Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response.
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Targeting filamin B induces tumor growth and metastasis via enhanced activity of matrix metalloproteinase-9 and secretion of VEGF-A.The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal disease.The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin ASignaling regulation and role of filamin A cleavage in Ca2+-stimulated migration of androgen receptor-deficient prostate cancer cells.Cytoskeletal Filamin A Differentially Modulates RNA Polymerase III Gene Transcription in Transformed Cell Lines.Unravelling a new mechanism linking actin polymerization and gene transcription.Filamin A interacts with the coactivator MKL1 to promote the activity of the transcription factor SRF and cell migration.A compendium of proteins that interact with HIF-1α.Hypoxia induces calpain activity and degrades SMAD2 to attenuate TGFβ signaling in macrophages.Discovery of Manassantin A Protein Targets Using Large-Scale Protein Folding and Stability Measurements.FLNA is implicated in pulmonary neuroendocrine tumors aggressiveness and progression.The putative involvement of actin-binding proteins and cytoskeleton proteins in pathological mechanisms of ketamine cystitis-Revealed by a prospective pilot study using proteomic approaches.Dysregulation of Calpain Proteolytic Systems Underlies Degenerative Vascular Disorders.Potential biomarkers and targets in reversibility of pulmonary arterial hypertension secondary to congenital heart disease: an explorative study.Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinibRNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure
P2860
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P2860
Hypoxia-induced and calpain-dependent cleavage of filamin A regulates the hypoxic response.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 February 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Hypoxia-induced and calpain-de ...... egulates the hypoxic response.
@en
Hypoxia-induced and calpain-de ...... egulates the hypoxic response.
@nl
type
label
Hypoxia-induced and calpain-de ...... egulates the hypoxic response.
@en
Hypoxia-induced and calpain-de ...... egulates the hypoxic response.
@nl
prefLabel
Hypoxia-induced and calpain-de ...... egulates the hypoxic response.
@en
Hypoxia-induced and calpain-de ...... egulates the hypoxic response.
@nl
P2093
P2860
P356
P1476
Hypoxia-induced and calpain-de ...... egulates the hypoxic response.
@en
P2093
Alex-Xianghua Zhou
Hidetaka Uramoto
Levent M Akyürek
Lorenz Poellinger
Pegah Rouhi
Teresa Pereira
Xiaowei Zheng
P2860
P304
P356
10.1073/PNAS.1320815111
P407
P50
P577
2014-02-03T00:00:00Z