Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis. - Wikidata - awgldk - TriplyDB

Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis.

Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis.

http://www.wikidata.org/entity/Q37600074

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Cellular ageing mechanisms in osteoarthritis Redox regulation of FoxO transcription factors The relationship of autophagy defects to cartilage damage during joint aging in a mouse model.FoxO transcription factors support oxidative stress resistance in human chondrocytes Transthyretin deposition in articular cartilage: a novel mechanism in the pathogenesis of osteoarthritis.Inflammatory biomarkers in osteoarthritis.Osteoarthritis year in review 2015: biology Histopathological analyses of murine menisci: implications for joint aging and osteoarthritis Transcriptional control of chondrocyte specification and differentiation.Inhibition of Autophagy Increases 2-Methoxyestradiol-Induced Cytotoxicity in SW1353 Chondrosarcoma Cells.Suppression of REDD1 in osteoarthritis cartilage, a novel mechanism for dysregulated mTOR signaling and defective autophagy TWIST1 induces MMP3 expression through up-regulating DNA hydroxymethylation and promotes catabolic responses in human chondrocytes.Suppression of Sestrins in aging and osteoarthritic cartilage: dysfunction of an important stress defense mechanism.Role of Fibulin 3 in Aging-Related Joint Changes and Osteoarthritis Pathogenesis in Human and Mouse Knee Cartilage.ASIC1a Promotes Acid-Induced Autophagy in Rat Articular Chondrocytes through the AMPK/FoxO3a Pathway.Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration.Transthyretin deposition promotes progression of osteoarthritis.Proteasomal function is impaired in human osteoarthritic chondrocytes and this can contribute to decreased SOX9 and aggrecan.Regulated in Development and DNA Damage Response 1 Deficiency Impairs Autophagy and Mitochondrial Biogenesis in Articular Cartilage and Increases the Severity of Experimental Osteoarthritis.Dysregulated circadian rhythm pathway in human osteoarthritis: NR1D1 and BMAL1 suppression alters TGF-β signaling in chondrocytes.Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis.

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Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis.

http://www.wikidata.org/entity/Q37600074

description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年學術文章

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2013年學術文章

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2013年學術文章

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name

Dysregulated FOXO transcriptio ...... e in aging and osteoarthritis.

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Dysregulated FOXO transcriptio ...... e in aging and osteoarthritis.

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type

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Dysregulated FOXO transcriptio ...... e in aging and osteoarthritis.

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Dysregulated FOXO transcriptio ...... e in aging and osteoarthritis.

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prefLabel

Dysregulated FOXO transcriptio ...... e in aging and osteoarthritis.

@en

Dysregulated FOXO transcriptio ...... e in aging and osteoarthritis.

@nl

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J.JOCA.2013.11.004

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Osteoarthritis and Cartilage

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Dysregulated FOXO transcriptio ...... e in aging and osteoarthritis.

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A Hasegawa

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H Asahara

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M K Lotz

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M Saito

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Y Akasaki

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Y Iwamoto

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P2860

Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function.

Stressing the role of FoxO proteins in lifespan and disease

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

Cytotoxic aggregation and amyloid formation by the myostatin precursor protein

Oxidative stress inhibits insulin-like growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK signaling pathways.

Upregulation of insulin-like growth factor I gene expression in the lesions of osteoarthritic human articular cartilage

FoxO1 is a positive regulator of bone formation by favoring protein synthesis and resistance to oxidative stress in osteoblasts

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10.1016/J.JOCA.2013.11.004

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