Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man.
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Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history.The human homologue of the mouse t-complex gene, TCP1, is located on chromosome 6 but is not near the HLA regionThe internal thioester and the covalent binding properties of the complement proteins C3 and C4Infectious diseases associated with complement deficiencies.Identification of two independent risk factors for lupus within the MHC in United Kingdom families.Genetic fixity in the human major histocompatibility complex and block size diversity in the class I region including HLA-E.Defining the role of the MHC in autoimmunity: a review and pooled analysisMajor histocompatibility complex haplotype studies in Ashkenazi Jewish patients with pemphigus vulgaris.Deficiencies of human complement component C4A and C4B and heterozygosity in length variants of RP-C4-CYP21-TNX (RCCX) modules in caucasians. The load of RCCX genetic diversity on major histocompatibility complex-associated disease.The genetics of systemic lupus erythematosus: putting the pieces together.A restriction fragment of the C2 gene is a unique marker for C2 deficiency and the uncommon C2 allele C2*B (a marker for type 1 diabetes)Major histocompatibility complex class III genes and susceptibility to immunoglobulin A deficiency and common variable immunodeficiency.Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patientsA critical assessment of the factors affecting reporter gene assays for promoter SNP function: a reassessment of -308 TNF polymorphism function using a novel integrated reporter systemGenetic linkage of IgA deficiency to the major histocompatibility complex: evidence for allele segregation distortion, parent-of-origin penetrance differences, and the role of anti-IgA antibodies in disease predisposition.Evolutionary analysis of classical HLA class I and II genes suggests that recent positive selection acted on DPB1*04:01 in Japanese population.Soma-to-germline feedback is implied by the extreme polymorphism at IGHV relative to MHC: The manifest polymorphism of the MHC appears greatly exceeded at Immunoglobulin loci, suggesting antigen-selected somatic V mutants penetrate Weismann's BarriePolymorphism of the human complement C4 and steroid 21-hydroxylase genes. Restriction fragment length polymorphisms revealing structural deletions, homoduplications, and size variants.Extended major histocompatibility complex haplotypes in patients with gluten-sensitive enteropathy.Biology of the human histocompatibility leukocyte antigen (HLA) system and a hypothesis regarding the generation of autoimmune diseasesHuman C4 haplotypes with duplicated C4A or C4BParental HLA compatibility, fetal wastage and neural tube defects: evidence for a T/t-like locus in humans.The immunological detection of a 21-OH deficiency mutation HLA supratype.The 6's and 17's of developmental mutants near the major histocompatibility complex: the mouse t-complex does not have a human equivalentDominant sequences of human major histocompatibility complex conserved extended haplotypes from HLA-DQA2 to DAXXIncomplete penetrance of susceptibility genes for MHC-determined immunoglobulin deficiencies in monozygotic twins discordant for type 1 diabetes.Gene copy-number variation and associated polymorphisms of complement component C4 in human systemic lupus erythematosus (SLE): low copy number is a risk factor for and high copy number is a protective factor against SLE susceptibility in European ACongruence as a measurement of extended haplotype structure across the genome.The immune response to hepatitis B vaccine in humans: inheritance patterns in families.Inherited predisposition to iridocyclitis with juvenile rheumatoid arthritis: selectivity among HLA-DR5 haplotypesIntrahaplotypic Variants Differentiate Complex Linkage Disequilibrium within Human MHC Haplotypes.Differences in gene copy number carried by different MHC ancestral haplotypes. Quantitation after physical separation of haplotypes by pulsed field gel electrophoresis.Extensive deletions and insertions in different MHC supratypes detected by pusled field gel electrophoresis.Linkage of pemphigus vulgaris antibody to the major histocompatibility complex in healthy relatives of patients.Immunogenomics: molecular hide and seek.Two genes encoding steroid 21-hydroxylase are located near the genes encoding the fourth component of complement in manSusceptibility locus for IgA deficiency and common variable immunodeficiency in the HLA-DR3, -B8, -A1 haplotypes.Assessment of complement C4 gene copy number using the paralog ratio test.Genetics of graft-versus-host disease: the major histocompatibility complex.Extreme genetic risk for type 1A diabetes in the post-genome era
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P2860
Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1983
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man.
@en
Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man.
@nl
type
label
Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man.
@en
Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man.
@nl
prefLabel
Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man.
@en
Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man.
@nl
P2093
P2860
P356
P1476
Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man.
@en
P2093
P2860
P304
P356
10.1073/PNAS.80.1.259
P407
P577
1983-01-01T00:00:00Z