Darinaparsin: a novel organic arsenical with promising anticancer activity.
about
From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemiaDarinaparsin is a multivalent chemotherapeutic which induces incomplete stress response with disruption of microtubules and Shh signalingThe novel arsenical Darinaparsin circumvents BRG1-dependent, HO-1-mediated cytoprotection in leukemic cellsDCPIP (2,6-dichlorophenolindophenol) as a genotype-directed redox chemotherapeutic targeting NQO1*2 breast carcinomaMetabolism, toxicity and anticancer activities of arsenic compounds.Dimethylarsinothioyl glutathione as a metabolite in human multiple myeloma cell lines upon exposure to DarinaparsinSilencing SATB1 inhibits the malignant phenotype and increases sensitivity of human osteosarcoma U2OS cells to arsenic trioxide.Arsenic Trioxide Activate Transcription of Heme Oxygenase-1 by Promoting Nuclear Translocation of NFE2L2.Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis.Anticancer activity of metal complexes: involvement of redox processes.Cellular redox pathways as a therapeutic target in the treatment of cancer.Therapeutic and analytical applications of arsenic binding to proteins.Prostate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signaling.Hedgehog Gli signalling in kidney fibrosis.Depletion of ALX1 causes inhibition of migration and induction of apoptosis in human osteosarcoma.Heme oxygenase-1 silencing increases the sensitivity of human osteosarcoma MG63 cells to arsenic trioxide.Arsenic trioxide induces apoptosis of p53 null osteosarcoma MG63 cells through the inhibition of catalase.Darinaparsin: solid tumor hypoxic cytotoxin and radiosensitizer.Monitoring Response and Resistance to the Novel Arsenical Darinaparsin in an AML Patient.Deciphering the molecular events during arsenic induced transcription signal cascade activation in cellular milieu.
P2860
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P2860
Darinaparsin: a novel organic arsenical with promising anticancer activity.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Darinaparsin: a novel organic arsenical with promising anticancer activity.
@en
Darinaparsin: a novel organic arsenical with promising anticancer activity.
@nl
type
label
Darinaparsin: a novel organic arsenical with promising anticancer activity.
@en
Darinaparsin: a novel organic arsenical with promising anticancer activity.
@nl
prefLabel
Darinaparsin: a novel organic arsenical with promising anticancer activity.
@en
Darinaparsin: a novel organic arsenical with promising anticancer activity.
@nl
P2093
P2860
P1476
Darinaparsin: a novel organic arsenical with promising anticancer activity.
@en
P2093
Barbara Wallner
Izidore S Lossos
Koren K Mann
Wilson H Miller
P2860
P304
P356
10.1517/13543780903282759
P407
P577
2009-11-01T00:00:00Z