A mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpC.
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Lysosomotropism depends on glucose: a chloroquine resistance mechanismEndolysosomal targeting of a clinical chlorin photosensitiser for light-triggered delivery of nano-sized medicines.Novel strategies to prevent the development of multidrug resistance (MDR) in cancer.Tumor stressors induce two mechanisms of intracellular p-glycoprotein-mediated resistance that are overcome by lysosomal-targeted thiosemicarbazones.Methotrexate Combined with 4-Hydroperoxycyclophosphamide Downregulates Multidrug-Resistance P-Glycoprotein Expression Induced by Methotrexate in Rheumatoid Arthritis Fibroblast-Like Synoviocytes via the JAK2/STAT3 Pathway.Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance.The thiosemicarbazone MeNNMe induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibitionMitochondrial-Targeting Anticancer Agent Conjugates and Nanocarrier Systems for Cancer Treatment
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A mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpC.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on December 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A mechanism for overcoming P-g ...... ilization using Dp44mT or DpC.
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A mechanism for overcoming P-g ...... ilization using Dp44mT or DpC.
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type
label
A mechanism for overcoming P-g ...... ilization using Dp44mT or DpC.
@en
A mechanism for overcoming P-g ...... ilization using Dp44mT or DpC.
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prefLabel
A mechanism for overcoming P-g ...... ilization using Dp44mT or DpC.
@en
A mechanism for overcoming P-g ...... ilization using Dp44mT or DpC.
@nl
P2860
P356
P1476
A mechanism for overcoming P-g ...... bilization using Dp44mT or DpC
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Patric J Jansson
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P356
10.1038/CDDIS.2016.381
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2016-12-01T00:00:00Z