Src kinases as therapeutic targets for cancer. - Wikidata - awgldk - TriplyDB

Src kinases as therapeutic targets for cancer.

Src kinases as therapeutic targets for cancer.

http://www.wikidata.org/entity/Q37604891

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Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis STATs: An Old Story, Yet Mesmerizing Early events in cell spreading as a model for quantitative analysis of biomechanical events Understanding the Biology of Bone Sarcoma from Early Initiating Events through Late Events in Metastasis and Disease Progression Phosphoregulation of the WAVE regulatory complex and signal integration SRC: marker or actor in prostate cancer aggressiveness EGF receptor trafficking: consequences for signaling and cancer Targeting Src family kinases in anti-cancer therapies: turning promise into triumph Tumor cell migration in complex microenvironments Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE.CIP4 promotes lung adenocarcinoma metastasis and is associated with poor prognosis.Crystal Structure of the Src Family Kinase Hck SH3-SH2 Linker Regulatory Region Supports an SH3-dominant Activation Mechanism Active site profiling reveals coupling between domains in SRC-family kinases Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab Review of Osteosarcoma and Current Management Fyn is induced by Ras/PI3K/Akt signaling and is required for enhanced invasion/migration Class III β-tubulin and the cytoskeletal gateway for drug resistance in ovarian cancer The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk Src activation plays an important key role in lymphomagenesis induced by FGFR1 fusion kinases Chromium genotoxicity: A double-edged sword Impacts of environmental toxicants on male reproductive dysfunction Characterization of in vivo keratin 19 phosphorylation on tyrosine-391 Barium promotes anchorage-independent growth and invasion of human HaCaT keratinocytes via activation of c-SRC kinase Global phosphotyrosine proteomics identifies PKCδ as a marker of responsiveness to Src inhibition in colorectal cancer The tyrosine kinase c-Src directly mediates growth factor-induced Notch-1 and Furin interaction and Notch-1 activation in pancreatic cancer cells The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in Platelets A Discovery Strategy for Selective Inhibitors of c-Src in Complex with the Focal Adhesion Kinase SH3/SH2-binding Region.SH2-catalytic domain linker heterogeneity influences allosteric coupling across the SFK family.Overexpression of atypical protein kinase C in HeLa cells facilitates macropinocytosis via Src activation Distinct effects of the mesenchymal dysplasia gene variant of murine Patched-1 protein on canonical and non-canonical Hedgehog signaling pathways Identification of two regions in the p140Cap adaptor protein that retain the ability to suppress tumor cell properties.Initial Segment Differentiation Begins During a Critical Window and Is Dependent upon Lumicrine Factors and SRC Proto-Oncogene (SRC) in the Mouse Macrophage motility requires distinct α5β1/FAK and α4β1/paxillin signaling events Network analysis of the focal adhesion to invadopodia transition identifies a PI3K-PKCα invasive signaling axis Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a Src-dependent fashion.An unexpected role for the clock protein timeless in developmental apoptosis Identification of potent Yes1 kinase inhibitors using a library screening approach.Conformational transition of membrane-associated terminally acylated HIV-1 Nef.Signal integration and gene induction by a functionally distinct STAT3 phosphoform.Targeting SRC in mucinous ovarian carcinoma.

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Src kinases as therapeutic targets for cancer.

http://www.wikidata.org/entity/Q37604891

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on October 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Src kinases as therapeutic targets for cancer.

@en

Src kinases as therapeutic targets for cancer.

@nl

type

label

Src kinases as therapeutic targets for cancer.

@en

Src kinases as therapeutic targets for cancer.

@nl

prefLabel

Src kinases as therapeutic targets for cancer.

@en

Src kinases as therapeutic targets for cancer.

@nl

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NRCLINONC.2009.129

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Nature Reviews Clinical Oncology

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Src kinases as therapeutic targets for cancer.

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Eric B Haura

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Lanxi Song

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Lori C Kim

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P2860

A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps

Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene.

RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity.

Cell adhesion receptors, tyrosine kinases and actin modulators: a complex three-way circuitry.

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nrclinonc.2009.129

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587-595

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scholarly article

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10.1038/NRCLINONC.2009.129

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10

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2009-10-01T00:00:00Z

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1011260533

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19787002

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