A monoclonal antibody against alphaVbeta3 integrin inhibits development of atherosclerotic lesions in diabetic pigs.
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Structural basis for pure antagonism of integrin αVβ3 by a high-affinity form of fibronectinEndocytic mechanism of internalization of dietary peptide lunasin into macrophages in inflammatory condition associated with cardiovascular diseaseThe arterial microenvironment: the where and why of atherosclerosis.Blocking αVβ3 integrin ligand occupancy inhibits the progression of albuminuria in diabetic rats.Blocking ligand occupancy of the αVβ3 integrin inhibits the development of nephropathy in diabetic pigsIntegrin β3 inhibition is a therapeutic strategy for supravalvular aortic stenosis.Insulin-like growth factor (IGF) binding protein 2 functions coordinately with receptor protein tyrosine phosphatase β and the IGF-I receptor to regulate IGF-I-stimulated signaling.Hyperglycemia stimulates p62/PKCζ interaction, which mediates NF-κB activation, increased Nox4 expression, and inflammatory cytokine activation in vascular smooth muscleRational design of a protein that binds integrin αvβ3 outside the ligand binding site.Positron emission tomography imaging of coronary atherosclerosis.Importance of receptor-targeted systems in the battle against atherosclerosis.Applying nanomedicine in maladaptive inflammation and angiogenesis.Developing Treatments for Chronic Kidney Disease in the 21st Century.The next generation of therapeutics for chronic kidney diseaseIntegrin signaling in atherosclerosis.αvβ3 Integrins Mediate Flow-Induced NF-κB Activation, Proinflammatory Gene Expression, and Early Atherogenic Inflammation.Under-expression of α8 integrin aggravates experimental atherosclerosis.Glucose regulation of thrombospondin and its role in the modulation of smooth muscle cell proliferationA turbulent path to plaque formation
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P2860
A monoclonal antibody against alphaVbeta3 integrin inhibits development of atherosclerotic lesions in diabetic pigs.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A monoclonal antibody against ...... otic lesions in diabetic pigs.
@en
A monoclonal antibody against ...... otic lesions in diabetic pigs.
@nl
type
label
A monoclonal antibody against ...... otic lesions in diabetic pigs.
@en
A monoclonal antibody against ...... otic lesions in diabetic pigs.
@nl
prefLabel
A monoclonal antibody against ...... otic lesions in diabetic pigs.
@en
A monoclonal antibody against ...... otic lesions in diabetic pigs.
@nl
P2093
P2860
P1476
A monoclonal antibody against ...... otic lesions in diabetic pigs.
@en
P2093
David R Clemmons
Dwight A Bellinger
Elizabeth P Merricks
Laura A Maile
Michael Rowland
Timothy C Nichols
Umadevi Veluvolu
Walker H Busby
P2860
P304
P356
10.1126/SCITRANSLMED.3000476
P407
P577
2010-02-01T00:00:00Z