Alternative splicing and genomic structure of the Wilms tumor gene WT1
about
Adenosine transporter ENT4 is a direct target of EWS/WT1 translocation product and is highly expressed in desmoplastic small round cell tumorThe zinc finger domain of Wilms' tumor 1 suppressor gene (WT1) behaves as a dominant negative, leading to abrogation of WT1 oncogenic potential in breast cancer cellsInhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1DENN, a novel human gene differentially expressed in normal and neoplastic cellsPAX8-mediated activation of the wt1 tumor suppressor geneWT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosisFunctionally distinct double-stranded RNA-binding domains associated with alternative splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminaseA novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1Analysis of the tumour suppressor genes, FHIT and WT-1, and the tumour rejection genes, BAGE, GAGE-1/2, HAGE, MAGE-1, and MAGE-3, in benign and malignant neoplasms of the salivary glandsRestoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotidesWT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomesMale sex determination: insights into molecular mechanismsWt-1 Expression Linked to Nitric Oxide Availability during Neonatal Obstructive NephropathyWilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B studyIdentification of WTAP, a novel Wilms' tumour 1-associating proteinThe Denys-Drash syndromeDNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemiaCoronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1.Transcriptional regulation by the Wilms tumor protein, Wt1, suggests a role of the metalloproteinase Adamts16 in murine genitourinary developmentPhysical and functional interaction between WT1 and p53 proteinsThe Wilms' tumor gene Wt1 is required for normal development of the retinaModulation of EWS/WT1 activity by the v-Src protein tyrosine kinase.The Wilms' tumor 1 (WT1) gene (+KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron.In silico regulatory analysis for exploring human disease progression.The Wilms' tumor gene product (WT1) modulates the response to 1,25-dihydroxyvitamin D3 by induction of the vitamin D receptor.Analysis of gene expression in prostate cancer epithelial and interstitial stromal cells using laser capture microdissection.A dominant mutation in the Wilms tumor gene WT1 cooperates with the viral oncogene E1A in transformation of primary kidney cells.Truncated WT1 mutants alter the subnuclear localization of the wild-type protein.Do intronic mutations affecting splicing of WT1 exon 9 cause Frasier syndrome?Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development.A TCR-mimic antibody to WT1 bypasses tyrosine kinase inhibitor resistance in human BCR-ABL+ leukemiasFrasier and Denys-Drash syndromes: different disorders or part of a spectrum?Tumor suppressor p53 can participate in transcriptional induction of the GADD45 promoter in the absence of direct DNA bindingAlternative splicing regulates distinct subcellular localization of Epithelial splicing regulatory protein 1 (Esrp1) isoforms.A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathwayMolecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis--a review.Presence of WT1, the Wilm's tumor suppressor gene product, in nuclear poly(A)(+) ribonucleoprotein.The predominant WT1 isoform (+KTS) encodes a DNA-binding protein targeting the planar cell polarity gene Scribble in renal podocytes.Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling.
P2860
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P2860
Alternative splicing and genomic structure of the Wilms tumor gene WT1
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh
1991年學術文章
@zh-hant
name
Alternative splicing and genomic structure of the Wilms tumor gene WT1
@en
Alternative splicing and genomic structure of the Wilms tumor gene WT1.
@nl
type
label
Alternative splicing and genomic structure of the Wilms tumor gene WT1
@en
Alternative splicing and genomic structure of the Wilms tumor gene WT1.
@nl
prefLabel
Alternative splicing and genomic structure of the Wilms tumor gene WT1
@en
Alternative splicing and genomic structure of the Wilms tumor gene WT1.
@nl
P2093
P2860
P356
P1476
Alternative splicing and genomic structure of the Wilms tumor gene WT1
@en
P2093
P2860
P304
P356
10.1073/PNAS.88.21.9618
P407
P577
1991-11-01T00:00:00Z