The actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer. - Wikidata - awgldk - TriplyDB

The actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer.

The actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer.

http://www.wikidata.org/entity/Q37614505

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Novel roles for actin in mitochondrial fission A novel small-molecule MRCK inhibitor blocks cancer cell invasion Myotonic dystrophy kinase-related Cdc42-binding kinases (MRCK), the ROCK-like effectors of Cdc42 and Rac1.Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy.Molecular pathways: targeting the kinase effectors of RHO-family GTPases.An apical MRCK-driven morphogenetic pathway controls epithelial polarity.Discovery of potent and selective MRCK inhibitors with therapeutic effect on skin cancer.RhoA, Rac1 and Cdc42 differentially regulate aSMA and collagen I expression in mesenchymal stem cells.

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P2860

The actin-myosin regulatory MRCK kinases: regulation, biological functions and associations with human cancer.

http://www.wikidata.org/entity/Q37614505

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 20 February 2014

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

The actin-myosin regulatory MR ...... ssociations with human cancer.

@en

The actin-myosin regulatory MR ...... ssociations with human cancer.

@nl

type

label

The actin-myosin regulatory MR ...... ssociations with human cancer.

@en

The actin-myosin regulatory MR ...... ssociations with human cancer.

@nl

prefLabel

The actin-myosin regulatory MR ...... ssociations with human cancer.

@en

The actin-myosin regulatory MR ...... ssociations with human cancer.

@nl

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S00109-014-1133-6

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Journal of Molecular Medicine

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The actin-myosin regulatory MR ...... ssociations with human cancer.

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Mathieu Unbekandt

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P2860

Intermolecular and intramolecular interactions regulate catalytic activity of myotonic dystrophy kinase-related Cdc42-binding kinase alpha

Activation of LIM kinases by myotonic dystrophy kinase-related Cdc42-binding kinase alpha

Phosphorylation of a novel myosin binding subunit of protein phosphatase 1 reveals a conserved mechanism in the regulation of actin cytoskeleton

Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding

Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase

Cloning and chromosomal location of a novel member of the myotonic dystrophy family of protein kinases

Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization

A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow

Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion

Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapy

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217-225

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scholarly article

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10.1007/S00109-014-1133-6

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92

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Michael F. Olson

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2014-02-20T00:00:00Z

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2014-03-01T00:00:00Z

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260271460

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cytoskeletal proteins

contractile proteins

macromolecular substances

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