Malignant peripheral nerve sheath tumour (MPNST): the clinical implications of cellular signalling pathways.
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Targeted therapies in sarcomas: challenging the challengeA RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressorPreclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imagingTargeting the PI3K/mTOR axis, alone and in combination with autophagy blockade, for the treatment of malignant peripheral nerve sheath tumorsCo-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity.Malignant Peripheral Nerve Sheath Tumors State of the Science: Leveraging Clinical and Biological Insights into Effective Therapies.TAGLN expression is upregulated in NF1-associated malignant peripheral nerve sheath tumors by hypomethylation in its promoter and subpromoter regions.EZH2-miR-30d-KPNB1 pathway regulates malignant peripheral nerve sheath tumour cell survival and tumourigenesisProtein expression of BIRC5, TK1, and TOP2A in malignant peripheral nerve sheath tumours--A prognostic test after surgical resection.Epidemiology and therapies for metastatic sarcomaMalignant peripheral nerve sheath tumors of the head and neck: a case series and literature reviewAntitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway.Wilms' tumor gene 1 (WT1) silencing inhibits proliferation of malignant peripheral nerve sheath tumor sNF96.2 cell line.A case of persistent foot pain in a neurofibromatosis type I patient.Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevanceNew developments in mammalian target of rapamycin inhibitors for the treatment of sarcomaFatty acid synthase is a metabolic oncogene targetable in malignant peripheral nerve sheath tumors.MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenancePhotothermal therapy improves the efficacy of a MEK inhibitor in neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors.Ras-driven transcriptome analysis identifies aurora kinase A as a potential malignant peripheral nerve sheath tumor therapeutic target.EGFR-STAT3 signaling promotes formation of malignant peripheral nerve sheath tumors.Preclinical therapeutic efficacy of a novel pharmacologic inducer of apoptosis in malignant peripheral nerve sheath tumors.Neurogenic tumors of soft tissue.New drugs in sarcomas.Antitumor effects of 4-methylumbelliferone, a hyaluronan synthesis inhibitor, on malignant peripheral nerve sheath tumor.An ShRNA Screen Identifies MEIS1 as a Driver of Malignant Peripheral Nerve Sheath Tumors.Targeting group I p21-activated kinases to control malignant peripheral nerve sheath tumor growth and metastasis.Evaluation of copy number variation and gene expression in neurofibromatosis type-1-associated malignant peripheral nerve sheath tumours.The NF1 gene in tumor syndromes and melanoma.Effect of triptolide on malignant peripheral nerve sheath tumours in vitro and in vivo.Response to sunitinib in combination with proton beam radiation in a patient with chondrosarcoma: a case report.Components of the eIF4F complex are potential therapeutic targets for malignant peripheral nerve sheath tumors and vestibular schwannomas.Molecular heterogeneity in malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1.Expression of 'drugable' tyrosine kinase receptors in malignant peripheral nerve sheath tumour: potential molecular therapeutic targets for a chemoresistant cancerIdentification of serum microRNAs in genome-wide serum microRNA expression profiles as novel noninvasive biomarkers for malignant peripheral nerve sheath tumor diagnosis.
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Malignant peripheral nerve sheath tumour (MPNST): the clinical implications of cellular signalling pathways.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 October 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Malignant peripheral nerve she ...... cellular signalling pathways.
@en
Malignant peripheral nerve sheath tumour
@nl
type
label
Malignant peripheral nerve she ...... cellular signalling pathways.
@en
Malignant peripheral nerve sheath tumour
@nl
prefLabel
Malignant peripheral nerve she ...... cellular signalling pathways.
@en
Malignant peripheral nerve sheath tumour
@nl
P2860
P1476
Malignant peripheral nerve she ...... cellular signalling pathways.
@en
P2093
Daniela Katz
P2860
P356
10.1017/S1462399409001227
P577
2009-10-19T00:00:00Z