Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies.
about
Discovering thiamine transporters as targets of chloroquine using a novel functional genomics strategyUnderstanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironmentCardiovascular autophagy: crossroads of pathology, pharmacology and toxicologyOptimizing treatments for lymphangioleiomyomatosisAutophagy in cancerChemoquiescence for ideal cancer treatment and prevention: where are we now?The Fab1/PIKfyve phosphoinositide phosphate kinase is not necessary to maintain the pH of lysosomes and of the yeast vacuole.The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their AlkalinizationFluorogenic Substrates for Visualizing Acidic Organelle Enzyme ActivitiesImproving chemical similarity ensemble approach in target predictionAdvances in the use of nanocarriers for cancer diagnosis and treatmentAutophagy- An emerging target for melanoma therapyManagement of lymphangioleiomyomatosisThe synergistic effect of everolimus and chloroquine on endothelial cell number reduction is paralleled by increased apoptosis and reduced autophagy occurrenceThymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cellsLysosomal function is involved in 17β-estradiol-induced estrogen receptor α degradation and cell proliferationAcute pretreatment with chloroquine attenuates renal I/R injury in ratsChloroquine is a zinc ionophoreAberrant DR5 transport through disruption of lysosomal function suggests a novel mechanism for receptor activationDHRSX, a novel non-classical secretory protein associated with starvation induced autophagyChloroquine sensitizes breast cancer cells to chemotherapy independent of autophagyPharmacokinetics and Toxicity in Rats and Monkeys of coDbait: A Therapeutic Double-stranded DNA Oligonucleotide Conjugated to CholesterolTargeting the PI3K/mTOR axis, alone and in combination with autophagy blockade, for the treatment of malignant peripheral nerve sheath tumorsAutophagy in oncogenic K-Ras promotes basal extrusion of epithelial cells by degrading S1PAutophagy inhibition for chemosensitization and radiosensitization in cancer: do the preclinical data support this therapeutic strategy?Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survivalChloroquine enhances the cytotoxicity of topotecan by inhibiting autophagy in lung cancer cellsProtective autophagy antagonizes oxaliplatin-induced apoptosis in gastric cancer cells.Repositioning: the fast track to new anti-malarial medicines?Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cellsA Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability.Defective autophagy is associated with neuronal injury in a mouse model of multiple sclerosisHydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer.Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenibHexokinase II inhibitor, 3-BrPA induced autophagy by stimulating ROS formation in human breast cancer cellsp53 and ARF: unexpected players in autophagy.Arene-Ru(II)-chloroquine complexes interact with DNA, induce apoptosis on human lymphoid cell lines and display low toxicity to normal mammalian cells.Direct, catalytic, and regioselective synthesis of 2-alkyl-, aryl-, and alkenyl-substituted N-heterocycles from N-oxides.Autophagy-regulating small molecules and their therapeutic applications.Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent.
P2860
Q21092414-86E065D9-D9A5-49F3-AEBC-136652D9CE10Q26852398-28590B71-6E0A-4D4A-9FCE-B7F33BBFDD43Q26858902-292B94AB-DDCE-457D-9B42-482282C2EC51Q26865250-23047D14-CAC1-4B1A-B519-F831EAE38E86Q26999216-76563579-5EBA-4FF5-BC3D-BCFC404BF1E2Q27026391-D2527603-9E4C-4C54-BC31-4E71791BE404Q27314340-2ADE5A8B-AE18-4FE6-964E-D8946E43A58CQ27318794-918D49FF-E648-4356-BDE1-8CD7A5E28D73Q27343082-D8F8C5FF-812F-4F9C-AD52-01079FB4AC14Q27902303-9E1EE5EA-124F-4745-B4DB-727D138360C9Q28070065-48142DCB-DA67-4FD7-B0CF-BCA006105424Q28071400-77B97233-9342-43F3-B4D1-E4020CAEDAEDQ28084725-FDB13C5A-D3DE-4558-97C3-5E10ED6CCB03Q28534969-394C9529-F18B-4DD1-9BE4-D597E56C08EBQ28536969-EFF4CC32-8DA0-4E0E-B0EA-0DDED6954BABQ28537915-356E5C67-D344-4A81-A85D-46B6FC22A93CQ28541693-F2A64B7B-DADA-41DE-A506-A4AE23875087Q28543470-451ED6D8-4B90-4605-B10C-165DAE89C185Q28817289-5D33991E-BE55-481A-A41F-F4D77D7DA750Q28854591-66FFE81C-9514-4561-9CF7-F81821DA95B3Q30513775-D1F647E4-8802-48BB-9A8D-D491A6797D1DQ30523973-99E112DF-D32C-4F4C-9289-E1F533FE0DFAQ30524134-CF24E8BE-81AE-4101-ADF5-A1B54C9F2076Q30572504-EB8FF13C-65C8-4561-B916-91E9796D242FQ30584653-854D5C9A-D893-4702-A038-50AF7D14E16DQ30611108-AB400FF2-6F68-4722-B631-BC611E9C5F1AQ33574951-F62664F3-BF56-4969-B523-C6447148620AQ33579758-D496459D-3697-4FFE-AA6D-89088910945AQ33612012-F9C6027A-1A0B-4AD3-807B-42E830961505Q33632727-7FCEA529-FC00-48AA-A2C8-25A65B6F22F7Q33759047-7042BAD9-D0F5-4EB4-86C7-CB1F571E59A1Q33808745-0C632863-8C7C-44BB-A784-A6C17F3405D0Q33813981-30D313D3-0DC8-453E-82AE-A8B7B8BB767AQ33878944-53145865-1646-4B62-A41F-66F69289E8B7Q33880100-4FB80FA0-DA1C-4B8E-B005-4847343BF727Q33936026-9F38492D-16DE-4427-A1B4-9588559BC964Q34020456-84B423DE-1C30-4D5F-AE54-73C028ADA5CBQ34053482-386B22B0-8AA6-49C1-A15A-39A9EC0D1D90Q34147157-325E7407-90C7-447D-A37C-D566DC356179Q34199557-E238E347-C9DA-4D43-BBAB-F9EAF1F8D0B2
P2860
Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 October 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Chloroquine and its analogs: a ...... ive and safe cancer therapies.
@en
Chloroquine and its analogs: a ...... ive and safe cancer therapies.
@nl
type
label
Chloroquine and its analogs: a ...... ive and safe cancer therapies.
@en
Chloroquine and its analogs: a ...... ive and safe cancer therapies.
@nl
prefLabel
Chloroquine and its analogs: a ...... ive and safe cancer therapies.
@en
Chloroquine and its analogs: a ...... ive and safe cancer therapies.
@nl
P1476
Chloroquine and its analogs: a ...... ive and safe cancer therapies.
@en
P2093
V Raja Solomon
P304
P356
10.1016/J.EJPHAR.2009.06.063
P407
P577
2009-10-15T00:00:00Z