Estrogen therapy: is time of initiation critical for neuroprotection?
about
Window of opportunity: estrogen as a treatment for ischemic strokeEstrogen effects on the brain: actions beyond the hypothalamus via novel mechanismsEstrogen receptors, the hippocampus, and memoryUtilizing induced pluripotent stem cells (iPSCs) to understand the actions of estrogens in human neuronsThe complexities of hormonal influences and risk of Parkinson's diseaseAn NO donor approach to neuroprotective and procognitive estrogen therapy overcomes loss of NO synthase function and potentially thrombotic riskEstrogens regulate neuroinflammatory genes via estrogen receptors α and β in the frontal cortex of middle-aged female ratsDifferential responses of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr) to 17β-estradiol and progesterone in hippocampal subregions that support synaptic remodeling and neurogenesisLIM kinase mediates estrogen action on the actin depolymerization factor CofilinHypersensitivity of the hippocampal CA3 region to stress-induced neurodegeneration and amyloidogenesis in a rat model of surgical menopause.Methods and baseline cardiovascular data from the Early versus Late Intervention Trial with Estradiol testing the menopausal hormone timing hypothesisConjugated equine estrogen, with medroxyprogesterone acetate, enhances formation of 5alpha-reduced progestogens and reduces anxiety-like behavior of middle-aged rats.Effects of global ischemia and estradiol pretreatment on phosphorylation of Akt, CREB and STAT3 in hippocampal CA1 of young and middle-aged female rats.Estrogen Effects on Cognitive and Synaptic Health Over the LifecourseEstrogens and cognition: Friends or foes?: An evaluation of the opposing effects of estrogens on learning and memory.Age- and hormone-regulation of opioid peptides and synaptic proteins in the rat dorsal hippocampal formation.II. Cognitive performance of middle-aged female rats is influenced by capacity to metabolize progesterone in the prefrontal cortex and hippocampus.Estrogen enhances neurogenesis and behavioral recovery after stroke.Neuroprotective actions of estradiol and novel estrogen analogs in ischemia: translational implicationsDonepezil plus estradiol treatment enhances learning and delay-dependent memory performance by young ovariectomized rats with partial loss of septal cholinergic neuronsDivergent mechanisms for trophic actions of estrogens in the brain and peripheral tissues.Mechanisms of estrogens' dose-dependent neuroprotective and neurodamaging effects in experimental models of cerebral ischemia.Differences in verbal memory performance in postmenopausal women receiving hormone therapy: 17β-estradiol versus conjugated equine estrogens.A mechanism emerges for the critical period hypothesis for estrogen treatmentC terminus of Hsc70-interacting protein (CHIP)-mediated degradation of hippocampal estrogen receptor-alpha and the critical period hypothesis of estrogen neuroprotection.Galanthamine plus estradiol treatment enhances cognitive performance in aged ovariectomized rats.Long-term cognitive impairment in older adult twins discordant for gynecologic cancer treatmentLong-term consequences of estrogens administered in midlife on female cognitive agingEstrogen neuroprotection and the critical period hypothesis.Oestrogen signalling and neuroprotection in cerebral ischaemia.Effects of long-term treatment with estrogen and medroxyprogesterone acetate on synapse number in the medial prefrontal cortex of aged female rats.The effects of long-term treatment with estradiol and medroxyprogesterone acetate on tyrosine hydroxylase fibers and neuron number in the medial prefrontal cortex of aged female rats.Potential Role of Oestrogen Modulation in the Treatment of Neurocognitive Deficits in SchizophreniaThe ageing cortical synapse: hallmarks and implications for cognitive declineEffects of estrogen and aging on the synaptic distribution of phosphorylated Akt-immunoreactivity in the CA1 region of the female rat hippocampus.Factors influencing the cognitive and neural effects of hormone treatment during aging in a rodent model.Cognitive response to estradiol in postmenopausal women is modified by high cortisol.Neuroprotective action of acute estrogens: animal models of brain ischemia and clinical implications.Menopausal Hormone Therapy, Age, and Chronic Diseases: Perspectives on Statistical Trends.Cognition, mood, and physiological concentrations of sex hormones in the early and late postmenopause
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P2860
Estrogen therapy: is time of initiation critical for neuroprotection?
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Estrogen therapy: is time of initiation critical for neuroprotection?
@en
Estrogen therapy: is time of initiation critical for neuroprotection?
@nl
type
label
Estrogen therapy: is time of initiation critical for neuroprotection?
@en
Estrogen therapy: is time of initiation critical for neuroprotection?
@nl
prefLabel
Estrogen therapy: is time of initiation critical for neuroprotection?
@en
Estrogen therapy: is time of initiation critical for neuroprotection?
@nl
P2860
P356
P1476
Estrogen therapy: is time of initiation critical for neuroprotection?
@en
P2093
Barbara B Sherwin
P2860
P2888
P304
P356
10.1038/NRENDO.2009.193
P577
2009-11-01T00:00:00Z