P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.
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Biology and therapy of inherited retinal degenerative disease: insights from mouse modelsChemistry and biology of the initial steps in vision: the Friedenwald lecture.A small molecule mitigates hearing loss in a mouse model of Usher syndrome IIIExclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa.Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations.Impact of reduced rhodopsin expression on the structure of rod outer segment disc membranesA High-Throughput Drug Screening Strategy for Detecting Rhodopsin P23H Mutant Rescue and Degradation.The G protein-coupled receptor rhodopsin: a historical perspectiveInherent instability of the retinitis pigmentosa P23H mutant opsin.Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration.High-throughput screening assays to identify small molecules preventing photoreceptor degeneration caused by the rhodopsin P23H mutation.The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control.The heat-shock response co-inducer arimoclomol protects against retinal degeneration in rhodopsin retinitis pigmentosa.Wild-type opsin does not aggregate with a misfolded opsin mutant.In vivo Editing of the Human Mutant Rhodopsin Gene by Electroporation of Plasmid-based CRISPR/Cas9 in the Mouse Retina.Transcriptome profiling of NIH3T3 cell lines expressing opsin and the P23H opsin mutant identifies candidate drugs for the treatment of retinitis pigmentosa.Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration.Phenotypic characterization of P23H and S334ter rhodopsin transgenic rat models of inherited retinal degeneration.The role of the ER stress-response protein PERK in rhodopsin retinitis pigmentosa.Cone-like rhodopsin expressed in the all-cone retina of the colubrid pine snake as a potential adaptation to diurnality.MicroRNA-processing Enzymes Are Essential for Survival and Function of Mature Retinal Pigmented Epithelial Cells in Mice.A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.Characterization of photoreceptor degeneration in the rhodopsin P23H transgenic rat line 2 using optical coherence tomography.Targeted disruption of the endogenous zebrafish locus as models of rapid rod photoreceptor degenerationThe crowns have eyes: multiple opsins found in the eyes of the crown-of-thorns starfish Acanthaster planci
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P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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name
P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.
@en
P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.
@nl
type
label
P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.
@en
P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.
@nl
prefLabel
P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.
@en
P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.
@nl
P2093
P2860
P356
P1476
P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis.
@en
P2093
Alexander V Kolesnikov
Sanae Sakami
Vladimir J Kefalov
P2860
P304
P356
10.1093/HMG/DDT561
P577
2013-11-07T00:00:00Z