Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancer.
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The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary FibrosisDiabetic Kidney Disease: Pathophysiology and Therapeutic TargetsSIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growthInhibition of BET bromodomains as a therapeutic strategy for cancer drug discoveryRole of mitochondrial dysfunction in cancer progressionA Novel Sirtuin-3 Inhibitor, LC-0296, Inhibits Cell Survival and Proliferation, and Promotes Apoptosis of Head and Neck Cancer CellsAssociations among Metabolism, Circadian Rhythm and Age-Associated DiseasesInduction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor activitySirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections.Overexpression of mitochondrial sirtuins alters glycolysis and mitochondrial function in HEK293 cells.Mitochondrial Lon protease at the crossroads of oxidative stress, ageing and cancer.Genetic and Functional Sequence Variants of the SIRT3 Gene Promoter in Myocardial InfarctionThe Prognostic and Clinicopathological Roles of Sirtuin-3 in Various Cancers.Pro-Proliferative Function of Mitochondrial Sirtuin Deacetylase SIRT3 in Human MelanomaProtective effects of sirtuin 3 in a murine model of sepsis-induced acute kidney injury.Estradiol via estrogen receptor beta influences ROS levels through the transcriptional regulation of SIRT3 in human seminoma TCam-2 cells.Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitroDifferentiation of human neuroblastoma cells toward the osteogenic lineage by mTOR inhibitorSirtuin 3 acts as a negative regulator of autophagy dictating hepatocyte susceptibility to lipotoxicity.SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis.Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer.Interplay Between SIRT-3, Metabolism and Its Tumor Suppressor Role in Hepatocellular Carcinoma.Sirtuins in Skin and Skin Cancers.SIRT3: Oncogene and Tumor Suppressor in Cancer.Sirtuin 1-dependent resveratrol cytotoxicity and pro-differentiation activity on breast cancer cells.Sirt3 attenuates doxorubicin-induced cardiac hypertrophy and mitochondrial dysfunction via suppression of Bnip3.Upregulation of mitochondrial NAD+ levels impairs the clonogenicity of SSEA1+ glioblastoma tumor-initiating cells.Power frequency magnetic field promotes a more malignant phenotype in neuroblastoma cells via redox-related mechanisms.Honokiol Induces Apoptosis, G1 Arrest, and Autophagy in KRAS Mutant Lung Cancer Cells.SIRT3 Silencing Sensitizes Breast Cancer Cells to Cytotoxic Treatments Through an Increment in ROS Production.Histone modifiers: Dynamic regulators of the cutaneous transcriptome.2-Methoxyestradiol Affects Mitochondrial Biogenesis Pathway and Succinate Dehydrogenase Complex Flavoprotein Subunit A in Osteosarcoma Cancer Cells.Mitochondrial energy metabolism and signalling in human glioblastoma cell lines with different PTEN gene status.Toxoplasma gondii GRA8 induces ATP5A1-SIRT3-mediated mitochondrial metabolic resuscitation: a potential therapy for sepsis.Crosstalk between gut microbiota and Sirtuin-3 in colonic inflammation and tumorigenesis.SIRT1 promotes formation of breast cancer through modulating Akt activity.Prognostic and clinicopathological value of SIRT3 expression in various cancers: a systematic review and meta-analysis.Cryptotanshinone suppresses cell proliferation and glucose metabolism via STAT3/SIRT3 signaling pathway in ovarian cancer cellsSirt3 enhances glioma cell viability by stabilizing Ku70–BAX interaction
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Sirtuin-3 (SIRT3), a therapeutic target with oncogenic and tumor-suppressive function in cancer.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 February 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Sirtuin-3 (SIRT3), a therapeut ...... uppressive function in cancer.
@en
Sirtuin-3 (SIRT3), a therapeut ...... uppressive function in cancer.
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type
label
Sirtuin-3 (SIRT3), a therapeut ...... uppressive function in cancer.
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Sirtuin-3 (SIRT3), a therapeut ...... uppressive function in cancer.
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prefLabel
Sirtuin-3 (SIRT3), a therapeut ...... uppressive function in cancer.
@en
Sirtuin-3 (SIRT3), a therapeut ...... uppressive function in cancer.
@nl
P2093
P2860
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P356
P1476
Sirtuin-3 (SIRT3), a therapeut ...... uppressive function in cancer.
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P2093
P2860
P356
10.1038/CDDIS.2014.14
P5008
P577
2014-02-06T00:00:00Z