Interplay between conformational selection and induced fit in multidomain protein-ligand binding probed by paramagnetic relaxation enhancement.
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Development of a method for reconstruction of crowded NMR spectra from undersampled time-domain dataBoth protein dynamics and ligand concentration can shift the binding mechanism between conformational selection and induced fitLocal isotropic diffusion approximation for coupled internal and overall molecular motions in NMR spin relaxation.Structure-function relationships in human testis-determining factor SRY: an aromatic buttress underlies the specific DNA-bending surface of a high mobility group (HMG) box.Conformational preferences underlying reduced activity of a thermophilic ribonuclease H.On the energy components governing molecular recognition in the framework of continuum approachesFlexible receptor docking for drug discovery.Hybrid Approaches to Structural Characterization of Conformational Ensembles of Complex Macromolecular Systems Combining NMR Residual Dipolar Couplings and Solution X-ray Scattering.Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions.Rate Constants and Mechanisms of Protein-Ligand Binding.Application of Site-Specific Spin Labeling for NMR Detecting Inhibitor-Induced Conformational Change of HIV-1 Reverse Transcriptase.Conformational Selection in a Protein-Protein Interaction Revealed by Dynamic Pathway Analysis.Activation processes in ligand-activated G protein-coupled receptors: A case study of the adenosine A2A receptor.A Dynamic Overview of Antimicrobial Peptides and Their Complexes
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P2860
Interplay between conformational selection and induced fit in multidomain protein-ligand binding probed by paramagnetic relaxation enhancement.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 31 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Interplay between conformation ...... gnetic relaxation enhancement.
@en
Interplay between conformation ...... gnetic relaxation enhancement.
@nl
type
label
Interplay between conformation ...... gnetic relaxation enhancement.
@en
Interplay between conformation ...... gnetic relaxation enhancement.
@nl
prefLabel
Interplay between conformation ...... gnetic relaxation enhancement.
@en
Interplay between conformation ...... gnetic relaxation enhancement.
@nl
P2860
P1476
Interplay between conformation ...... agnetic relaxation enhancement
@en
P2093
G Marius Clore
P2860
P356
10.1016/J.BPC.2013.08.006
P577
2013-08-31T00:00:00Z