Vesicular transport is not required for the cytoplasmic pool of cholera toxin to interact with the stimulatory alpha subunit of the heterotrimeric g protein.
about
A therapeutic chemical chaperone inhibits cholera intoxication and unfolding/translocation of the cholera toxin A1 subunitHsp90 is required for transfer of the cholera toxin A1 subunit from the endoplasmic reticulum to the cytosol.The cholera toxin A1(3) subdomain is essential for interaction with ADP-ribosylation factor 6 and full toxic activity but is not required for translocation from the endoplasmic reticulum to the cytosolCo- and post-translocation roles for HSP90 in cholera Intoxication.Protein-disulfide isomerase displaces the cholera toxin A1 subunit from the holotoxin without unfolding the A1 subunitSubstrate-induced unfolding of protein disulfide isomerase displaces the cholera toxin A1 subunit from its holotoxin.Structural and functional interactions between the cholera toxin A1 subunit and ERdj3/HEDJ, a chaperone of the endoplasmic reticulum.Inhibition of Cholera Toxin and Other AB Toxins by Polyphenolic Compounds.Lipid rafts alter the stability and activity of the cholera toxin A1 subunit.Thermal Unfolding of the Pertussis Toxin S1 Subunit Facilitates Toxin Translocation to the Cytosol by the Mechanism of Endoplasmic Reticulum-Associated Degradation.Conformational instability of the cholera toxin A1 polypeptide
P2860
Q28477818-C133D957-649F-4014-919F-1F4399D76F82Q34181280-8F0BFCCF-CF17-4FED-8FA1-4A314F2394C8Q34492828-21FADBAC-417F-4027-9B69-C08025C0189FQ34580417-A1ECEB74-6F38-4C44-BFAD-8C7B57FD3160Q35063023-DBBA3FCA-CDCD-4F19-A088-0BA64B4EFE94Q35091242-A2EBF642-D0EA-4884-B120-B0BEAE6785F4Q35671627-9CB3F876-945D-457B-93AC-260F74D754BAQ36187443-5A01D0AD-6304-4263-AD77-61BE4C74F4DBQ36216662-43690475-300F-496E-96A8-0E0B531BFF7BQ37424978-3043FF21-FF17-473B-BFD6-063286357294Q41835060-1E87F00A-C654-41D2-A59D-54B8E1A00B08
P2860
Vesicular transport is not required for the cytoplasmic pool of cholera toxin to interact with the stimulatory alpha subunit of the heterotrimeric g protein.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Vesicular transport is not req ...... the heterotrimeric g protein.
@en
Vesicular transport is not req ...... the heterotrimeric g protein.
@nl
type
label
Vesicular transport is not req ...... the heterotrimeric g protein.
@en
Vesicular transport is not req ...... the heterotrimeric g protein.
@nl
prefLabel
Vesicular transport is not req ...... the heterotrimeric g protein.
@en
Vesicular transport is not req ...... the heterotrimeric g protein.
@nl
P2860
P1476
Vesicular transport is not req ...... f the heterotrimeric g protein
@en
P2093
Randall K Holmes
P2860
P304
P356
10.1128/IAI.72.12.6826-6835.2004
P407
P577
2004-12-01T00:00:00Z