Prediction of solubility and permeability class membership: provisional BCS classification of the world's top oral drugs
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How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionDarunavir: a critical review of its properties, use and drug interactionsOral delivery of lipophilic drugs: the tradeoff between solubility increase and permeability decrease when using cyclodextrin-based formulationsMechanistic insight into the dramatic improvement of probucol dissolution in neutral solutions by solid dispersion in Eudragit E PO with saccharin.Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdlesProvisional in-silico biopharmaceutics classification (BCS) to guide oral drug product development.3D Printing technologies for drug delivery: a review.Statistics on BCS classification of generic drug products approved between 2000 and 2011 in the USA.The Effect of Excipients on the Permeability of BCS Class III Compounds and Implications for Biowaivers.Factors to consider in developing individual pharmaceutical product quality risk profiles useful to government procurement agencies.Summary of the National Institute of Child Health and Human Development-best pharmaceuticals for Children Act Pediatric Formulation Initiatives Workshop-Pediatric Biopharmaceutics Classification System Working Group.Bile salt/phospholipid mixed micelle precursor pellets prepared by fluid-bed coating.Pediatric Biopharmaceutical Classification System: Using Age-Appropriate Initial Gastric Volume.From bench to humans: formulation development of a poorly water soluble drug to mitigate food effectCyclodextrin-poly(anhydride) nanoparticles as new vehicles for oral drug delivery.The solubility-permeability interplay and its implications in formulation design and development for poorly soluble drugs.Current regulatory approaches of bioequivalence testing.Targeted prodrugs in oral drug delivery: the modern molecular biopharmaceutical approach.A primer for best practices in tissue preparation for bioanalysis.Mechanisms of absorption and elimination of drugs administered by inhalation.Impact of pharmaceutical cocrystals: the effects on drug pharmacokinetics.Alginate Particles as Platform for Drug Delivery by the Oral Route: State-of-the-Art.A critical review of properties of darunavir and analytical methods for its determination.Drug nanosuspensions: a ZIP tool between traditional and innovative pharmaceutical formulations.Nanoformulation strategies for the enhanced oral bioavailability of antiretroviral therapeutics.Challenges and Strategies in Thermal Processing of Amorphous Solid Dispersions: A ReviewThermal Processing of PVP- and HPMC-Based Amorphous Solid Dispersions.Use of Polyvinyl Alcohol as a Solubility Enhancing Polymer for Poorly Water-Soluble Drug Delivery (Part 2)Use of Polyvinyl Alcohol as a Solubility-Enhancing Polymer for Poorly Water Soluble Drug Delivery (Part 1).Distinguishing between the permeability relationships with absorption and metabolism to improve BCS and BDDCS predictions in early drug discoveryMechanistic prediction of food effects for Compound A tablet using PBPK model.Oral drug therapy following bariatric surgery: an overview of fundamentals, literature and clinical recommendations.Applications of Polymers as Pharmaceutical Excipients in Solid Oral Dosage Forms.A proposed food breakdown classification system to predict food behavior during gastric digestion.A mini-review of non-parenteral clonidine preparations for paediatric sedation.RYGB and Drug Disposition: How to Do Better? Analysis of Pharmacokinetic Studies and Recommendations for Clinical Practice.Hydrotropic Solubilization of Lipophilic Drugs for Oral Delivery: The Effects of Urea and Nicotinamide on Carbamazepine Solubility-Permeability Interplay.Enabling the intestinal absorption of highly polar antiviral agents: ion-pair facilitated membrane permeation of zanamivir heptyl ester and guanidino oseltamivir.Regional-dependent intestinal permeability and BCS classification: elucidation of pH-related complexity in rats using pseudoephedrine.The twofold advantage of the amorphous form as an oral drug delivery practice for lipophilic compounds: increased apparent solubility and drug flux through the intestinal membrane.
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Prediction of solubility and permeability class membership: provisional BCS classification of the world's top oral drugs
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 October 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Prediction of solubility and p ...... of the world's top oral drugs
@en
Prediction of solubility and p ...... of the world's top oral drugs.
@nl
type
label
Prediction of solubility and p ...... of the world's top oral drugs
@en
Prediction of solubility and p ...... of the world's top oral drugs.
@nl
prefLabel
Prediction of solubility and p ...... of the world's top oral drugs
@en
Prediction of solubility and p ...... of the world's top oral drugs.
@nl
P2093
P2860
P1433
P1476
Prediction of solubility and p ...... of the world's top oral drugs
@en
P2093
Arik Dahan
Gordon L Amidon
Jonathan M Miller
P2860
P2888
P304
P356
10.1208/S12248-009-9144-X
P407
P577
2009-10-30T00:00:00Z
P5875
P6179
1043278894