Targeting Akt3 signaling in triple-negative breast cancer.
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Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4Maximising the potential of AKT inhibitors as anti-cancer treatmentsCurcumin Suppresses Proliferation and Migration of MDA-MB-231 Breast Cancer Cells through Autophagy-Dependent Akt DegradationKinMap: a web-based tool for interactive navigation through human kinome dataRegulation of PI3K effector signalling in cancer by the phosphoinositide phosphatasesGiant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunitRegulation of miRNA-29c and its downstream pathways in preneoplastic progression of triple-negative breast cancer.Akt3 is responsible for the survival and proliferation of embryonic stem cellsSignaling specificity in the Akt pathway in biology and disease.Astrocyte elevated gene-1 interacts with Akt isoform 2 to control glioma growth, survival, and pathogenesis.Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation.Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer.Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines.Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors.Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathwaysSystematic Identification and Assessment of Therapeutic Targets for Breast Cancer Based on Genome-Wide RNA Interference TranscriptomesA streamlined method for the design and cloning of shRNAs into an optimized Dox-inducible lentiviral vector.AKT signaling in ERBB2-amplified breast cancer.Circular RNA ZNF609 functions as a competitive endogenous RNA to regulate AKT3 expression by sponging miR-150-5p in Hirschsprung's disease.Signalling specificity in the Akt pathway in breast cancer.Upregulation of AKT3 Confers Resistance to the AKT Inhibitor MK2206 in Breast Cancer.Micro-ribonucleic acid 29b inhibits cell proliferation and invasion and enhances cell apoptosis and chemotherapy effects of cisplatin via targeting of DNMT3b and AKT3 in prostate cancerMetabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer.Suppression of SPIN1-mediated PI3K-Akt pathway by miR-489 increases chemosensitivity in breast cancer.The roles of akt isoforms in the regulation of podosome formation in fibroblasts and extracellular matrix invasion.ERβ1 inversely correlates with PTEN/PI3K/AKT pathway and predicts a favorable prognosis in triple-negative breast cancer.Potential therapeutic targets of triple-negative breast cancer based on its intrinsic subtype.Amplification of Chromosome 1q Genes Encoding the Phosphoinositide Signalling Enzymes PI4KB, AKT3, PIP5K1A and PI3KC2B in Breast Cancer.The crossroads of breast cancer progression: insights into the modulation of major signaling pathways.AKT3 drives adenoid cystic carcinoma development in salivary glands.In search of AKT kinase inhibitors as anticancer agents: structure-based design, docking, and molecular dynamics studies of 2,4,6-trisubstituted pyridines.Dysregulation of AKT3 along with a small panel of mRNAs stratifies high-grade serous ovarian cancer from both normal epithelia and benign tumor tissues.Leptin Signaling Mediates Obesity-associated CSC Enrichment and EMT in Preclinical TNBC Models.Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing.Vav1 down-modulates Akt in different breast cancer subtypes: a new promising chance to improve breast cancer outcome.Role of Akt Isoforms Controlling Cancer Stem Cell Survival, Phenotype and Self-Renewal.Involvement of multiple cellular pathways in regulating resistance to tamoxifen in BIK-suppressed MCF-7 cells.MicroRNA‑497 inhibits cellular proliferation, migration and invasion of papillary thyroid cancer by directly targeting AKT3.MicroRNA-433 targets AKT3 and inhibits cell proliferation and viability in breast cancer.Potential tumor suppressing role of microRNA-545 in epithelial ovarian cancer.
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P2860
Targeting Akt3 signaling in triple-negative breast cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 December 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Targeting Akt3 signaling in triple-negative breast cancer.
@en
Targeting Akt3 signaling in triple-negative breast cancer.
@nl
type
label
Targeting Akt3 signaling in triple-negative breast cancer.
@en
Targeting Akt3 signaling in triple-negative breast cancer.
@nl
prefLabel
Targeting Akt3 signaling in triple-negative breast cancer.
@en
Targeting Akt3 signaling in triple-negative breast cancer.
@nl
P2093
P2860
P1433
P1476
Targeting Akt3 signaling in triple-negative breast cancer
@en
P2093
Alex Toker
Andrew H Beck
Andriy Marusyk
Kornelia Polyak
Taku Yoshida
P2860
P304
P356
10.1158/0008-5472.CAN-13-2175
P407
P50
P577
2013-12-12T00:00:00Z