Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy. - Wikidata - awgldk - TriplyDB

Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy.

Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy.

http://www.wikidata.org/entity/Q37626117

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Hepatic glucose and lipid metabolism.Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice.Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling.Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia High-sensitivity, broadband-decoupled (13) C MR spectroscopy in humans at 7T using two-dimensional heteronuclear single-quantum coherence.The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes (13)C MRS of human brain at 7 Tesla using [2-(13)C]glucose infusion and low power broadband stochastic proton decoupling.Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver.Bonded Cumomer Analysis of Human Melanoma Metabolism Monitored by 13C NMR Spectroscopy of Perfused Tumor Cells (13)C MRS and LC-MS Flux Analysis of Tumor Intermediary Metabolism.Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism.Stable isotope-based flux studies in nonalcoholic fatty liver disease.Beyond the paradigm: Combining mass spectrometry and nuclear magnetic resonance for metabolomics.Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.Model-Based Assessment of Plasma Citrate Flux Into the Liver: Implications for NaCT as a Therapeutic Target Response to burgess.Mitochondrial genome architecture in non-alcoholic fatty liver disease.Tracer-based assessments of hepatic anaplerotic and TCA cycle flux: practicality, stoichiometry, and hidden assumptions.Assessment of Hepatic Mitochondrial Oxidation and Pyruvate Cycling in NAFLD by (13)C Magnetic Resonance Spectroscopy.Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA).Hepatic mTORC1 Opposes Impaired Insulin Action to Control Mitochondrial Metabolism in Obesity Limitations of detection of anaplerosis and pyruvate cycling from metabolism of [1-(13)C] acetate.Ultra-high-field magnetic resonance spectroscopy in non-alcoholic fatty liver disease: Novel mechanistic and diagnostic insights of energy metabolism in non-alcoholic steatohepatitis and advanced fibrosis.Determination of Fatty Acid Oxidation and Lipogenesis in Mouse Primary Hepatocytes.Measurement of 13 C turnover into glutamate and glutamine pools in brain tumor patients.Multiorgan, Multimodality Imaging in Cardiometabolic Disease.Synthesis of Unsaturated Precursors for Parahydrogen-Induced Polarization and Molecular Imaging of 1-13C-Acetates and 1-13C-Pyruvates via Side Arm Hydrogenation.Deuterium metabolic imaging (DMI) for MRI-based 3D mapping of metabolism in vivo

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Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy.

http://www.wikidata.org/entity/Q37626117

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 08 December 2013

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

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vědecký článek

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name

Direct assessment of hepatic m ...... gnetic resonance spectroscopy.

@en

Direct assessment of hepatic m ...... gnetic resonance spectroscopy.

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type

label

Direct assessment of hepatic m ...... gnetic resonance spectroscopy.

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Direct assessment of hepatic m ...... gnetic resonance spectroscopy.

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Direct assessment of hepatic m ...... gnetic resonance spectroscopy.

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Direct assessment of hepatic m ...... gnetic resonance spectroscopy.

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Nature Medicine

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Direct assessment of hepatic m ...... gnetic resonance spectroscopy.

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Douglas E Befroy

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Douglas L Rothman

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Gary W Cline

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Jeff K Trimmer

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Julia Brosnan

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Nimit Jain

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Rachel J Perry

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Sylvie Dufour

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P2860

Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy

Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

Evaluation of cerebral acetate transport and metabolic rates in the rat brain in vivo using 1H-[13C]-NMR

An integrated (2)H and (13)C NMR study of gluconeogenesis and TCA cycle flux in humans.

Glucose production, gluconeogenesis, and hepatic tricarboxylic acid cycle fluxes measured by nuclear magnetic resonance analysis of a single glucose derivative.

Use of 2H2O for estimating rates of gluconeogenesis. Application to the fasted state.

Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism

Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients.

Liver ATP synthesis is lower and relates to insulin sensitivity in patients with type 2 diabetes.

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10.1038/NM.3415

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Gerald I. Shulman

Kitt Falk Petersen

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