Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors.
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New strategies to maximize therapeutic opportunities for NAMPT inhibitors in oncologyExpanding antitumor therapeutic windows by targeting cancer-specific nicotinamide adenine dinucleotide phosphate-biogenesis pathwaysRedox control of glutamine utilization in cancerThe complex landscape of pancreatic cancer metabolismNew option for the initial management of metastatic pancreatic cancer?Expression of nicotinamide phosphoribosyltransferase-influenced genes predicts recurrence-free survival in lung and breast cancers.Resveratrol differentially regulates NAMPT and SIRT1 in Hepatocarcinoma cells and primary human hepatocytes.SIRT1-Activating Compounds (STAC) Negatively Regulate Pancreatic Cancer Cell Growth and Viability Through a SIRT1 Lysosomal-Dependent PathwayCD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.Metabonomic changes from pancreatic intraepithelial neoplasia to pancreatic ductal adenocarcinoma in tissues from rats.Targeting metabolic scavenging in pancreatic cancer.A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT.Inhibition of Nicotinamide Phosphoribosyltransferase Induces Apoptosis in Estrogen Receptor-Positive MCF-7 Breast Cancer Cells.EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells.Rewiring carbohydrate catabolism differentially affects survival of pancreatic cancer cell lines with diverse metabolic profiles.Nicotinamide phosphoribosyltransferase (Nampt) in carcinogenesis: new clinical opportunities.NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone.Effect of bafilomycin and NAADP on membrane-associated ATPases and respiration of isolated mitochondria of the murine Nemeth-Kellner lymphoma.Nampt/PBEF/visfatin upregulation in colorectal tumors, mirrored in normal tissue and whole blood of colorectal cancer patients, is associated with metastasis, hypoxia, IL1β, and anemia.Compartmentation of metabolites in regulating epigenome of cancer.Rho GTPase effectors and NAD metabolism in cancer immune suppression.CD38 enhances the proliferation and inhibits the apoptosis of cervical cancer cells by affecting the mitochondria functions.Targeting the vulnerability to NAD+ depletion in B-cell acute lymphoblastic leukemia.Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer.Molecular and functional analysis of anchorage independent, treatment-evasive neuroblastoma tumorspheres with enhanced malignant properties: A possible explanation for radio-therapy resistance.Novel agents for pancreatic ductal adenocarcinoma: emerging therapeutics and future directions.Reconstruction of a generic metabolic network model of cancer cells.Quantitative Analysis of NAD Synthesis-Breakdown Fluxes.Expression of NAMPT is associated with breast invasive ductal carcinoma development and prognosis.A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD DeclineReciprocal Regulation of Metabolic Reprogramming and Epigenetic Modifications in CancerCD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD Pools
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Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Targeting of NAD metabolism in ...... therapy for pancreatic tumors.
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Targeting of NAD metabolism in ...... therapy for pancreatic tumors.
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type
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Targeting of NAD metabolism in ...... therapy for pancreatic tumors.
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Targeting of NAD metabolism in ...... therapy for pancreatic tumors.
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prefLabel
Targeting of NAD metabolism in ...... therapy for pancreatic tumors.
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Targeting of NAD metabolism in ...... therapy for pancreatic tumors.
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P2093
P2860
P1476
Targeting of NAD metabolism in ...... therapy for pancreatic tumors
@en
P2093
Anatilde M Gonzalez Guerrico
Carlos Escande
Claudia C S Chini
Eduardo N Chini
Maria Thereza Barbosa
Veronica Nin
P2860
P304
P356
10.1158/1078-0432.CCR-13-0150
P407
P577
2013-09-11T00:00:00Z