Transcription-generated torsional stress destabilizes nucleosomes.
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DNA topology and transcriptionEffects of DNA supercoiling on chromatin architectureRNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription.Controlling gene expression by DNA mechanics: emerging insights and challenges.Genome urbanization: clusters of topologically co-regulated genes delineate functional compartments in the genome of Saccharomyces cerevisiae.Doxorubicin, DNA torsion, and chromatin dynamics.Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response GenesTopoisomerase 1 inhibition reversibly impairs synaptic function.Torsion-mediated interaction between adjacent genesRNA processing factors Swd2.2 and Sen1 antagonize RNA Pol III-dependent transcription and the localization of condensin at Pol III genesTopoisomerase I deficiency causes RNA polymerase II accumulation and increases AID abundance in immunoglobulin variable genesThe Genetic Map Enters Its Second CenturyTopoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.CENP-A and H3 Nucleosomes Display a Similar Stability to Force-Mediated Disassembly.Meeting report: 11th EMBL conference on transcription and chromatin - August 23-26, 2014 - Heidelberg, Germany.Absence of canonical marks of active chromatin in developmentally regulated genesForces, fluctuations, and self-organization in the nucleusGenome-wide profiling of nucleosome sensitivity and chromatin accessibility in Drosophila melanogaster.The role of ATP-dependent machines in regulating genome topology.Integrated molecular mechanism directing nucleosome reorganization by human FACTNoncoding Transcription Is a Driving Force for Nucleosome Instability in spt16 Mutant CellsTopoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.Topological diversity of chromatin fibers: Interplay between nucleosome repeat length, DNA linking number and the level of transcriptionDNA supercoiling during transcription.DNA torsion as a feedback mediator of transcription and chromatin dynamics.Transcription and recombination: when RNA meets DNA.High-resolution digital profiling of the epigenome.Role of genome guardian proteins in transcriptional elongation.The Importance of Controlling Transcription Elongation at Coding and Noncoding RNA Loci.Effects of DNA supercoiling on chromatin architecture.Torsional behavior of chromatin is modulated by rotational phasing of nucleosomes.topIb, a phylogenetic hallmark gene of Thaumarchaeota encodes a functional eukaryote-like topoisomerase IB.The transcriptional regulator Aire binds to and activates super-enhancers.Chromatin regulates DNA torsional energy via topoisomerase II-mediated relaxation of positive supercoils.Zylka et al. reply.Nucleosome stability measured in situ by automated quantitative imaging.Anthracyclines induce double-strand DNA breaks at active gene promoters.Investigating DNA supercoiling in eukaryotic genomes.Dissecting the Roles of Divergent and Convergent Transcription in Chromosome Instability.Sequence-dependent response of DNA to torsional stress: a potential biological regulation mechanism.
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Transcription-generated torsional stress destabilizes nucleosomes.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 08 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Transcription-generated torsional stress destabilizes nucleosomes.
@en
Transcription-generated torsional stress destabilizes nucleosomes.
@nl
type
label
Transcription-generated torsional stress destabilizes nucleosomes.
@en
Transcription-generated torsional stress destabilizes nucleosomes.
@nl
prefLabel
Transcription-generated torsional stress destabilizes nucleosomes.
@en
Transcription-generated torsional stress destabilizes nucleosomes.
@nl
P2860
P356
P1476
Transcription-generated torsional stress destabilizes nucleosomes
@en
P2093
Steven Henikoff
P2860
P2888
P356
10.1038/NSMB.2723
P577
2013-12-08T00:00:00Z