Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy
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You eat what you are: autophagy inhibition as a therapeutic strategy in leukemiaPrognosis and management of acute myeloid leukemia in patients with Down syndromeInhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cellsHistone deacetylase inhibitor trichostatin A enhances the antitumor effect of the oncolytic adenovirus H101 on esophageal squamous cell carcinoma in vitro and in vivo.Novel small-molecule SIRT1 inhibitors induce cell death in adult T-cell leukaemia cellsGATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia.LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia.Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia.Angiotensin II type 1 receptor blocker telmisartan induces apoptosis and autophagy in adult T-cell leukemia cells.Pharmacologic agents targeting autophagy.HDAC Family Members Intertwined in the Regulation of Autophagy: A Druggable Vulnerability in Aggressive Tumor Entities.ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells.miR-99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFβ and Wnt signaling.Epigenetic alterations in acute myeloid leukemias.Detection of Autophagy Induction After HDAC Inhibitor Treatment in Leukemic Cells.How do tumor cells respond to HDAC inhibition?miR-139-5p controls translation in myeloid leukemia through EIF4G2.Autophagy Proteins ATG5 and ATG7 Are Essential for the Maintenance of Human CD34(+) Hematopoietic Stem-Progenitor Cells.Herpes simplex virus 1 interferes with autophagy of murine dendritic cells and impairs their ability to stimulate CD8+ T lymphocytes.Basal autophagy is pivotal for Hodgkin and Reed-Sternberg cells' survival and growth revealing a new strategy for Hodgkin lymphoma treatmentAtg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia.Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance.Preserved High Probability of Overall Survival with Significant Reduction of Chemotherapy for Myeloid Leukemia in Down Syndrome: A Nationwide Prospective Study in Japan.Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia.Activation of autophagy by FOXO3 regulates redox homeostasis during osteogenic differentiation.Histone Deacetylase Inhibitor-Induced Autophagy in Tumor Cells: Implications for p53.The histone deacetylase inhibitor givinostat (ITF2357) exhibits potent anti-tumor activity against CRLF2-rearranged BCP-ALL.Naturally occurring benzoic acid derivatives retard cancer cell growth by inhibiting histone deacetylases (HDAC).miR-9 is a tumor suppressor in pediatric AML with t(8;21).p53-Mediated Molecular Control of Autophagy in Tumor Cells.Histone deacetylase inhibitor ITF2357 leads to apoptosis and enhances doxorubicin cytotoxicity in preclinical models of human sarcoma.Acute myeloid leukemia in children: Current status and future directions.The impact of Mir-9 regulation in normal and malignant hematopoiesis.The small molecule STF-62247 induces apoptotic and autophagic cell death in leukemic cells.Epigenetic Regulation of Autophagy: A Path to the Control of AutoimmunityNovel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines
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Histone deacetylase inhibitors induce apoptosis in myeloid leukemia by suppressing autophagy
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Histone deacetylase inhibitors ...... kemia by suppressing autophagy
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Histone deacetylase inhibitors ...... emia by suppressing autophagy.
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type
label
Histone deacetylase inhibitors ...... kemia by suppressing autophagy
@en
Histone deacetylase inhibitors ...... emia by suppressing autophagy.
@nl
prefLabel
Histone deacetylase inhibitors ...... kemia by suppressing autophagy
@en
Histone deacetylase inhibitors ...... emia by suppressing autophagy.
@nl
P2093
P2860
P921
P356
P1433
P1476
Histone deacetylase inhibitors ...... kemia by suppressing autophagy
@en
P2093
B Kumar Thakur
D Panayotova-Dimitrova
D Reinhardt
G M N Behrens
J Schoening
K Heitmann
M El Khatib
M Leverkus
M V Stankov
P2860
P2888
P304
P356
10.1038/LEU.2013.264
P577
2013-09-12T00:00:00Z