Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer.
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The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activityEstrogen and xenoestrogens in breast cancerFrequent expression of new cancer/testis gene D40/AF15q14 in lung cancers of smokersThe molecular basis of lung cancer: molecular abnormalities and therapeutic implicationsDown-regulation of interferon regulatory factor 4 gene expression in leukemic cells due to hypermethylation of CpG motifs in the promoter regionDNA Methyltransferase Activity Assays: Advances and ChallengesNew 5' regions of the murine and human genes for DNA (cytosine-5)-methyltransferaseCharacterization of the human DNA methyltransferase splice variant Dnmt1bInactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum sampleshNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencingAssociation of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expressionHigh-risk myelodysplastic syndromes and hypermethylation of the p15Ink4B gene.DNA methyltransferases: a novel target for prevention and therapy.Investigating the epigenetic effects of a prototype smoke-derived carcinogen in human cellsSpontaneously immortalised bovine mammary epithelial cells exhibit a distinct gene expression pattern from the breast cancer cellsDNA methylation changes and multiple myeloma.Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production.Cigarette smoking and p16INK4α gene promoter hypermethylation in non-small cell lung carcinoma patients: a meta-analysis.Ornithine decarboxylase antizyme induces hypomethylation of genome DNA and histone H3 lysine 9 dimethylation (H3K9me2) in human oral cancer cell line.Reduced expression of IRF7 in nasal epithelial cells from smokers after infection with influenza.Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality.DNA methylation, chromatin inheritance, and cancer.Increased NQO1 but not c-MET and survivin expression in non-small cell lung carcinoma with KRAS mutationsSuppression of TET1-dependent DNA demethylation is essential for KRAS-mediated transformation.DNA methylation, imprinting and cancer.Polymorphism of DNA methyltransferase 3B -149C/T and cancer risk: a meta-analysisIdentification of kazinol Q, a natural product from Formosan plants, as an inhibitor of DNA methyltransferase.Epigenetic cancer therapies: DNA methyltransferase inhibitors.DNA methylation and gene silencing in cancer: which is the guilty party?Epigenetic inactivation of heparan sulfate (glucosamine) 3-O-sulfotransferase 2 in lung cancer and its role in tumorigenesis.Expression and methylation of mitochondrial transcription factor a in chronic obstructive pulmonary disease patients with lung cancer.NNK-induced DNA methyltransferase 1 in lung tumorigenesis in A/J mice and inhibitory effects of (-)-epigallocatechin-3-gallate.Retinoblastoma pathway dysregulation causes DNA methyltransferase 1 overexpression in cancer via MAD2-mediated inhibition of the anaphase-promoting complexDetection of DNA methyltransferase activity using allosteric molecular beacons.Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide.RFTS-deleted DNMT1 enhances tumorigenicity with focal hypermethylation and global hypomethylationCigarette smoke condensate and individual constituents modulate DNA methyltransferase expression in human liver cells.DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell linesIdentification of DLC-1 expression and methylation status in patients with non-small-cell lung cancer.Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
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P2860
Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Increased cytosine DNA-methylt ...... an early event in lung cancer.
@en
Increased cytosine DNA-methylt ...... an early event in lung cancer.
@nl
type
label
Increased cytosine DNA-methylt ...... an early event in lung cancer.
@en
Increased cytosine DNA-methylt ...... an early event in lung cancer.
@nl
prefLabel
Increased cytosine DNA-methylt ...... an early event in lung cancer.
@en
Increased cytosine DNA-methylt ...... an early event in lung cancer.
@nl
P2093
P2860
P356
P1476
Increased cytosine DNA-methylt ...... an early event in lung cancer.
@en
P2093
K J Nikula
S A Belinsky
S B Baylin
P2860
P304
P356
10.1073/PNAS.93.9.4045
P407
P577
1996-04-01T00:00:00Z