DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster.

DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster.

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http://www.wikidata.org/entity/Q37629380
MicroRNAs of the mir-17~92 cluster regulate multiple aspects of pancreatic tumor development and progression.A new PDAC mouse model originated from iPSCs-converted pancreatic cancer stem cells (CSCcm).Methyl-CpG-binding domain 3 inhibits epithelial-mesenchymal transition in pancreatic cancer cells via TGF-β/Smad signalling.microRNA regulation of human pancreatic cancer stem cells.Epigenetic inhibition of miR-663b by long non-coding RNA HOTAIR promotes pancreatic cancer cell proliferation via up-regulation of insulin-like growth factor 2.Expression, regulation and mechanism of action of the miR-17-92 cluster in tumor cells (Review).Repurposing Established Compounds to Target Pancreatic Cancer Stem Cells (CSCs).The Ever-Evolving Concept of the Cancer Stem Cell in Pancreatic Cancer.Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors.Curcumol Controls Choriocarcinoma Stem-Like Cells Self-Renewal via Repression of DNA Methyltransferase (DNMT)- and Histone Deacetylase (HDAC)-Mediated Epigenetic Regulation.From Chemotherapy to Combined Targeted Therapeutics: In Vitro and in Vivo Models to Decipher Intra-tumor Heterogeneity.DNA-Methyltransferase 1 Induces Dedifferentiation of Pancreatic Cancer Cells through Silencing of Krüppel-Like Factor 4 Expression.DNMT1 ablation suppresses tumorigenesis by inhibiting the self-renewal of esophageal cancer stem cells.
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DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster.

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http://www.wikidata.org/entity/Q37629380
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 June 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
DNMT1 Inhibition Reprograms Pa ...... tion of the miR-17-92 Cluster.
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DNMT1 Inhibition Reprograms Pa ...... tion of the miR-17-92 Cluster.
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DNMT1 Inhibition Reprograms Pa ...... tion of the miR-17-92 Cluster.
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DNMT1 Inhibition Reprograms Pa ...... tion of the miR-17-92 Cluster.
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DNMT1 Inhibition Reprograms Pa ...... tion of the miR-17-92 Cluster.
@en
DNMT1 Inhibition Reprograms Pa ...... tion of the miR-17-92 Cluster.
@nl
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DNMT1 Inhibition Reprograms Pa ...... tion of the miR-17-92 Cluster.
@en
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P2860
P304
P31
P356
10.1158/0008-5472.CAN-15-3268
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