Multidrug efflux pumps: the structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues.
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The lipid translocase, ABCA4: seeing is believing.Access Path to the Ligand Binding Pocket May Play a Role in Xenobiotics Selection by AhRJump into a New Fold-A Homology Based Model for the ABCG2/BCRP Multidrug TransporterDimerization of ABCG2 analysed by bimolecular fluorescence complementation.The DrrAB efflux system of Streptomyces peucetius is a multidrug transporter of broad substrate specificityDrug resistance is conferred on the model yeast Saccharomyces cerevisiae by expression of full-length melanoma-associated human ATP-binding cassette transporter ABCB5.Protein contacts and ligand binding in the inward-facing model of human P-glycoprotein.An asymmetric post-hydrolysis state of the ABC transporter ATPase dimer.ATP-Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening.Three-dimensional structure of the human breast cancer resistance protein (BCRP/ABCG2) in an inward-facing conformation.Dynamics of a bacterial multidrug ABC transporter in the inward- and outward-facing conformationsThe ABCG family of membrane-associated transporters: you don't have to be big to be mightyMechanism of the ABC transporter ATPase domains: catalytic models and the biochemical and biophysical record.Diversity in ABC transporters: type I, II and III importers.Mechanistic diversity in ATP-binding cassette (ABC) transporters.Impact of the Recent Mouse P-Glycoprotein Structure for Structure-Based Ligand Design.Multiple resistance to carcinogens and xenobiotics: P-glycoproteins as universal detoxifiers.Role of the juxtamembrane region of cytoplasmic loop 3 in the gating and conductance of the cystic fibrosis transmembrane conductance regulator chloride channel.Time-resolved Fourier transform infrared spectroscopy of the nucleotide-binding domain from the ATP-binding Cassette transporter MsbA: ATP hydrolysis is the rate-limiting step in the catalytic cycle.Identification of residues in ABCG2 affecting protein trafficking and drug transport, using co-evolutionary analysis of ABCG sequences.Identification and utilization of two important transporters: SgvT1 and SgvT2, for griseoviridin and viridogrisein biosynthesis in Streptomyces griseoviridis.Molecular insight into conformational transmission of human P-glycoprotein.Substrate versus inhibitor dynamics of P-glycoprotein.Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis.The flexibility of P-glycoprotein for its poly-specific drug binding from molecular dynamics simulations
P2860
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P2860
Multidrug efflux pumps: the structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 December 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Multidrug efflux pumps: the st ...... -glycoproteins and homologues.
@en
Multidrug efflux pumps: the st ...... -glycoproteins and homologues.
@nl
type
label
Multidrug efflux pumps: the st ...... -glycoproteins and homologues.
@en
Multidrug efflux pumps: the st ...... -glycoproteins and homologues.
@nl
prefLabel
Multidrug efflux pumps: the st ...... -glycoproteins and homologues.
@en
Multidrug efflux pumps: the st ...... -glycoproteins and homologues.
@nl
P2860
P1433
P1476
Multidrug efflux pumps: the st ...... P-glycoproteins and homologues
@en
P2093
Peter M Jones
P2860
P304
P356
10.1111/J.1742-4658.2009.07486.X
P407
P577
2009-12-03T00:00:00Z