The RON receptor tyrosine kinase promotes metastasis by triggering MBD4-dependent DNA methylation reprogramming.
about
Distinctive properties of metastasis-initiating cellsEpigenetic determinants of metastasisMBD4 interacts with and recruits USP7 to heterochromatic fociFor robust big data analyses: a collection of 150 important pro-metastatic genesMetabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIPAptamers Binding to c-Met Inhibiting Tumor Cell MigrationPreclinical Efficacy of Ron Kinase Inhibitors Alone and in Combination with PI3K Inhibitors for Treatment of sfRon-Expressing Breast Cancer Patient-Derived Xenografts.Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFREmerging concept in DNA methylation: role of transcription factors in shaping DNA methylation patterns.5-hydroxymethylcytosine: a potential therapeutic target in cancer.Methyl-CpG-binding domain proteins: readers of the epigenome.Deregulation of splicing factors and breast cancer development.Chronic oxidative stress causes estrogen-independent aggressive phenotype, and epigenetic inactivation of estrogen receptor alpha in MCF-7 breast cancer cells.The Tyrosine Kinome Dictates Breast Cancer Heterogeneity and Therapeutic Responsiveness.Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization.The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury.hnRNP A1-mediated translational regulation of the G quadruplex-containing RON receptor tyrosine kinase mRNA linked to tumor progression.RON Signaling Is a Key Mediator of Tumor Progression in Many Human Cancers.RON tyrosine kinase mutations in brain metastases from lung cancer.Epigenetic silencing of RNF144A expression in breast cancer cells through promoter hypermethylation and MBD4.mTORC1 is a key mediator of RON-dependent breast cancer metastasis with therapeutic potential
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The RON receptor tyrosine kinase promotes metastasis by triggering MBD4-dependent DNA methylation reprogramming.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 02 January 2014
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The RON receptor tyrosine kina ...... DNA methylation reprogramming.
@en
The RON receptor tyrosine kina ...... DNA methylation reprogramming.
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type
label
The RON receptor tyrosine kina ...... DNA methylation reprogramming.
@en
The RON receptor tyrosine kina ...... DNA methylation reprogramming.
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prefLabel
The RON receptor tyrosine kina ...... DNA methylation reprogramming.
@en
The RON receptor tyrosine kina ...... DNA methylation reprogramming.
@nl
P2093
P2860
P1433
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The RON receptor tyrosine kina ...... DNA methylation reprogramming.
@en
P2093
Alana L Welm
Elizabeth A Goossen
Mark J Mulvihill
Mark R Albertella
Stuart Thomson
Stéphanie Cunha
Yi-Chun Lin
P2860
P304
P356
10.1016/J.CELREP.2013.12.010
P577
2014-01-02T00:00:00Z